Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]
, 2020 OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S +4 more
core +1 more source
Current Issues in Molecular Biology, 2023 Nicotinamide riboside (NR), a precursor of nicotinamide adenine dinucleotide (NAD+), has been studied to support human health against metabolic stress, cardiovascular disease, and neurodegenerative disease.
Ibuki Arizono +8 more
doaj +1 more source
Prescription drug forms with midazolam [PDF]
Farmacja Polska, 2021 Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
doaj +1 more source
Toxicokinetics of fumonisin B1 in turkey poults and tissue persistence after exposure to a diet containing the maximum European tolerance for fumonisins in avian feeds [PDF]
, 2008 The kinetic of fumonisin B1 (FB1) after a single IV and oral dose, and FB1 persistence in tissue were investigated in turkey poults by HPLC after purification of samples on columns.
Bailly, Jean Denis +4 more
core +1 more source
Secondary failure of oral therapy in patients with type 2 diabetes: How to overcome it? [PDF]
Scripta MedicaBackground/Aim: Secondary failure of oral therapy occurs after a long period of successful use of oral antidiabetic drugs. The exact mechanism of its occurrence is not known.
Marković Aleksandra +4 more
doaj +1 more source
Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration under Similar Systemic Exposures [PDF]
, 2019 Objective To test whether an individual's subjective responses to alcohol are similar when the breath alcohol concentration (BrAC) trajectory resulting from oral administration is matched by intravenous administration.
Boes, Julian +6 more
core +1 more source
Metabolic profile, bioavailability and toxicokinetics of zearalenone-14-glucoside in rats after oral and intravenous administration by liquid chromatography high-resolution mass spectrometry and tandem mass spectrometry [PDF]
, 2019 Zearalenone-14-glucoside (ZEN-14G), a key modified mycotoxin, has attracted a great deal of attention due to the possible conversion to its free form of zearalenone (ZEN) exerting toxicity.
De Boevre, Marthe +9 more
core +1 more source
Pharmaceutics, 2020 Oral drug administration to pediatric patients is characterized by a lack of age-appropriate drug products and the off-label use of medicines. However, drug administration practices at hospital wards is a scarcely studied subject.
Maria Rautamo +5 more
doaj +1 more source
Intravenous Voriconazole after Toxic Oral Administration [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not.
Alffenaar, J.W.C. +5 more
openaire +2 more sources
Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid
Pharmaceutics, 2021 Mycophenolic acid (MPA) is commonly used for organ rejection prophylaxis via oral administration in the clinic. Recent studies have shown that MPA also has anticancer activities. To explore new therapeutic options for oral precancerous/cancerous lesions,
Xiuqing Gao +7 more
doaj +1 more source