Results 221 to 230 of about 34,804 (275)
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Alprazolam Kinetics Following Sublingual and Oral Administration
Journal of Clinical Psychopharmacology, 1987Thirteen healthy volunteers received 1 mg of alprazolam, as the commercially available oral tablet, by sublingual and oral routes on two occasions in random sequence. Plasma alprazolam concentrations during 48 hours after each dose were measured by electron-capture gas-liquid chromatography.
J M, Scavone +2 more
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Ocular hypotensive effect of sublingual administration of timolol
International Ophthalmology, 1997A randomized clinical, trial to assess ocular hypotensive effect of sublingual administration of timolol was performed.Seventeen (9 male, 8 female; age range 45 to 68 years) with bilateral ocular hypertension were selected for the study. Each patient was evaluated with regard to IOP, arterial blood pressure and heart rate before and after each of the ...
QUARANTA, Luciano +5 more
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γ-Cyclodextrin: Testosterone Complex Suitable for Sublingual Administration
Journal of Pharmaceutical Sciences, 1987A crystalline complex of testosterone with gamma-cyclodextrin was evaluated for solubility and dissolution rate. Whereas these parameters were at least an order of magnitude lower than those of testosterone complexes with amorphous derivatives of cyclodextrins, the properties of the crystalline complex enabled the preparation of a suitable ...
J, Pitha, E J, Anaissie, K, Uekama
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Pharmacokinetic aspects of the sublingual administration of vincamine
Biopharmaceutics & Drug Disposition, 1990AbstractThe sublingual absorption of vincamine used as tracer occurs in two successive absorption steps: true sublingual absorption and absorption in the gastrointestinal tract of the drug dissolved in the saliva and not absorbed through the buccal mucosa. This is confirmed by a pharmacokinetic study and simulation. These two successive absorptions can
J M, Aiache +5 more
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Cost of allergy immunotherapy: sublingual vs subcutaneous administration
International Forum of Allergy & Rhinology, 2012AbstractBackground:Allergy immunotherapy is an effective way to manage the allergic patient and may be administered either through the subcutaneous route (SCIT) or the sublingual route (SLIT). Both have been proven efficacious; however, SLIT is currently not covered by insurance companies and is an out‐of‐pocket expense.
Kristin, Seiberling +4 more
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Symptomatic bradycardia following the administration of sublingual nitroglycerin
The American Journal of Emergency Medicine, 1993A case of severe bradycardia with junctional escape immediately following sublingual nitroglycerin is described. Bradycardia is a rare, but well-documented, complication of nitroglycerin and is often reported in the setting of myocardial ischemia or infarction.
R, Buckley, R, Roberts
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Arterial hypoxemia following the administration of sublingual nitroglycerin
American Heart Journal, 1978The effect of nitroglycerin on arterial blood gases and cardiovascular hemodynamics were studied in patients with coronary artery disease. In 13 premedicated patients blood gases and cardiovascular hemodynamics were studied before and 10 minutes after sublingual nitroglycerin (0.6 mg).
E A, Kopman +3 more
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Myocardial infarction following sublingual administration of isosorbide dinitrate
International Journal of Cardiology, 1990A 78-year-old with healed septal necrosis suffered a recurrent myocardial infarction of the anterior wall following the administration of isosorbide dinitrate 5 mg sublingually. After detailing the course of events, we discuss the role of paradoxical coronary spasm and hypotension-mediated myocardial ischemia occurring downstream to significant ...
S, Scardi, B, Zingone, C, Pandullo
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Triazolam Pharmacokinetics After Intravenous, Oral, and Sublingual Administration
Journal of Clinical Psychopharmacology, 1995This study was designed to evaluate the relative and absolute bioavailability of triazolam, 0.25 mg, after the administration of the marketed oral tablet and a sublingual prototype wafer; an intravenous dose was used as a reference. Twelve men were evaluated in a three-way crossover study; study days were separated by 1 week.
P D, Kroboth +4 more
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The sublingual administration of curare.
California medicine, 2003A new method of administering d-tubocurarine transmucosally by sublingual pellets (and also by rectal suppository) was used in 100 patients. In therapeutic dosage of 6 to 12 mg., it was found to be non-toxic and very effective in relieving pain due to acute and chronic muscle spasm.
W B, NEFF, H, MAYER
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