Results 51 to 60 of about 7,880,769 (355)
The contemporary city between administration and geomanagement [PDF]
Geographica Pannonica, 2013 The city, judged from the perspective of complexity sciences and tackled in a functionalist manner, is seen by many as a living organism, which is a geosystem that tends towards a finality, called sense of existence.
Bogdan-Nicolae Păcurar, Vasile Surd
doaj
Smart City: From Concept To Implementation
Wroclaw Review of Law, Administration and Economics, 2020 This article presents four interpretations of the term smart city, which are not competitive with each other, but even so, municipal authorities knowingly choose the so-called strong preference, as well as shows the conditions for implementing Smart City
Chrisidu-Budnik Agnieszka +1 more
doaj +1 more source
Molecular Therapy, 2010 In an attempt to treat cancer patients with ERBB2 overexpressing tumors, we developed a chimeric antigen receptor (CAR) based on the widely used humanized monoclonal antibody (mAb) Trastuzumab (Herceptin).
R. Morgan +5 more
semanticscholar +1 more source
The Road Ahead for the U.S. Auto Industry [PDF]
, 2005 [Excerpt] In 2004, U.S. light vehicle sales were up slightly, reversing a moderate slide that began in 2001. The 1.3 percent gain brought the market total to 16.8 million units, approximately the same level as 2002, and the fourth highest sales on record.
International Trade Administration, U.S. Department of Commerce
core +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
International Brazilian Journal of Urology, 2009 Purpose: The main objective of the investigation was to develop a transdermal therapeutic system for alfuzosin hydrochloride and to study the effects of polymeric system and loading dose on the in vitro skin permeation pattern.
Satyanarayan Pattnaik +4 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Internal Control of the Public Administration Bodies (Institutions) in the Republic of Macedonia
EIRP Proceedings, 2012 The main objective of this paper is to address a significant segment of public administration whichis in direct contact with citizens and more often seen as a main violator of human rights and citizens.
Fadil Zendeli
doaj