Results 71 to 80 of about 9,197,462 (314)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Parisians write to the Administration: Interplay between social and spatial boundaries (1920-1945)
L'Atelier du CRHThis article combines two of Isabelle Backouche’s current research topics. One is the annexation of the non aedificandi zone, a strip of land 250 meters wide where construction was banned in 1841 because it ran along the fortifications; it was largely ...
Isabelle Backouche
doaj +1 more source
Significance of Pirogov`s scientific ideas for modern organization of Public Health.
Medičnì Perspektivi, 2015 This article is about Nikolay Ivanovich Pirogov, a surgeon and anatomist, prominent scientist and educator, founder of field surgery. He was the first to learn field surgery and military administration in practice.
L. S. Semenova, U. A. Koryagin
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
THE BOUNDARIES OF THE FIRM. THE CASE OF OIL INDUSTRY IN ROMANIA [PDF]
The economic theory of the firm has met an exponential growth in the last decades different from the traditional neoclassical approach. In the first part of the paper we are skimming through the most spread approaches, namely the theory of incomplete ...
Dudian Monica +4 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Journal of Education and Health PromotionManagers should have the necessary competencies to achieve organizational goals. Employees have worked with different managers and have valid opinions about managerial competencies.
Parisa Yoshari +3 more
doaj +1 more source
Tabularia, 2011 Significations of excommunication are a neglected source for administrative history, yet their diplomatic provides valuable information. This paper examines significations issued by English bishops from the dioceses of Coventry and Lichfield, Exeter ...
Philippa Hoskin
doaj +1 more source
THE ROLE OF THE NECESSITY AND THE OPPORTUNITY ENTREPRENEURSHIP IN ECONOMIC DEVELOPMENT [PDF]
Entrepreneurship is a complex subject of study and its determinants, characteristics, dynamics and manifestations differ across countries. The level of economic development constitutes the contextual distinction for the research on entrepreneurship ...
Anca Bratu +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source