From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The quality of public administration performance is closely related to the issues of ethics in public administration [PDF]
When discussing the quality of public administration performance, it is necessary to comprehend its direct relation to the issues of ethics in the sphere of public administration.
Nečadová, Věra
core +1 more source
The "Problem" of Aspects of Teaching and Learning / Teaching - Learning in European Union Law
The paper addresses an important problem and the frequency of teaching and learning/teaching-learning in higher education/university student, generated by the incapacity to himself selectively information conveyed through alternative sources.
Nedelcu-Ienei Anda Veronica
doaj +1 more source
Significance of Pirogov`s scientific ideas for modern organization of Public Health.
This article is about Nikolay Ivanovich Pirogov, a surgeon and anatomist, prominent scientist and educator, founder of field surgery. He was the first to learn field surgery and military administration in practice.
L. S. Semenova, U. A. Koryagin
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Sabine River Compact Administration...Annual Report for the Year...
Annual report for the Sabine River Compact Administration for 1998, including a summary of the meetings and work of the administration, reports from the hydrologic stations, fiscal revenues and expenditures, and accompanying ...
Sabine River Compact Administration
core
2011, Fifty Seventh Annual Report: Sabine River Compact Administration, Louisiana and Texas [PDF]
Annual report for the Sabine River Compact Administration for 2011, including a summary of the meetings and work of the administration, reports from the hydrologic stations, fiscal revenues and expenditures, and accompanying ...
Sabine River Compact Administration
core
Parisians write to the Administration: Interplay between social and spatial boundaries (1920-1945)
This article combines two of Isabelle Backouche’s current research topics. One is the annexation of the non aedificandi zone, a strip of land 250 meters wide where construction was banned in 1841 because it ran along the fortifications; it was largely ...
Isabelle Backouche
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

