Results 91 to 100 of about 2,473,945 (261)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

İşveren Markasının İnsan Kaynakları Süreçleri Üzerine Etkileri

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2019
Küreselleşme sürecinin etkilerinin arttığı işgücü piyasalarında, şirketler için büyük önem arz eden konuların başında gelen İnsan Kaynakları Yönetimi; şirketin gelecek hedeflerine ulaşabilmesi, şirket verimliliğinin sağlanması ve artırılması için ihtiyaç
Mehmet Güler
doaj  

Leader Self-Efficacy of Women Intercollegiate Athletic Administrators

open access: yesJournal of Intercollegiate Sport, 2016
We tested a range of facilitating and inhibiting antecedents of leader self-efficacy on a large sample of 692 women intercollegiate athletic administrators in National Collegiate Athletic Association registered institutions. Drawing from social cognitive
Moe Machida-Kosuga   +2 more
doaj   +1 more source

Children at Works Progress Administration Feeding Program

open access: yes, 1936
Young African American children at a feeding program at Butler County Emergency School, a Works Progress Administration program ...
Sam Kremer for the Works Progress Administration (Photographer)
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Ontology of Urban Governance: A Framework for Pathways to Sustainable Urban Transition

open access: yesUrban Science
Evidence on urban governance has expanded but is fragmented and inadequate. It fails to articulate the complexity of urban governance in a way that would facilitate effective urban transitions.
Susanna Ghosh Mitra   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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