Results 81 to 90 of about 4,924,405 (317)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The "Problem" of Aspects of Teaching and Learning / Teaching - Learning in European Union Law

open access: yesJournal of Legal Studies, 2015
The paper addresses an important problem and the frequency of teaching and learning/teaching-learning in higher education/university student, generated by the incapacity to himself selectively information conveyed through alternative sources.
Nedelcu-Ienei Anda Veronica
doaj   +1 more source

Significance of Pirogov`s scientific ideas for modern organization of Public Health.

open access: yesMedičnì Perspektivi, 2015
This article is about Nikolay Ivanovich Pirogov, a surgeon and anatomist, prominent scientist and educator, founder of field surgery. He was the first to learn field surgery and military administration in practice.
L. S. Semenova, U. A. Koryagin
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Parisians write to the Administration: Interplay between social and spatial boundaries (1920-1945)

open access: yesL'Atelier du CRH
This article combines two of Isabelle Backouche’s current research topics. One is the annexation of the non aedificandi zone, a strip of land 250 meters wide where construction was banned in 1841 because it ran along the fortifications; it was largely ...
Isabelle Backouche
doaj   +1 more source

Year-end ... statistics of the National Credit Union Administration.

open access: yes, 1981
Mode of access ...
United States. National Credit Union Administration.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Delineating the Development of English episcopal chanceries through the Signification of Excommunication

open access: yesTabularia, 2011
Significations of excommunication are a neglected source for administrative history, yet their diplomatic provides valuable information. This paper examines significations issued by English bishops from the dioceses of Coventry and Lichfield, Exeter ...
Philippa Hoskin
doaj   +1 more source

Estate Administration Program. Russian

open access: yes, 2004
Covers OCLC #879580175, OCLC #1375677756Mode of access: Internet from the Oregon Government Publications Collection.Text in Russian.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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