Results 111 to 120 of about 2,473,945 (261)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Other title: Republican River Compact Administration Documents, 2011-2013

, 2011
application/pdfThis is an incomplete collection of documents by and about the Republican River Compact Administration and the Republican River Compact from 2011 through 2013.
Republican River Compact Administration.
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Irrigation administration report.

Mode of access: Internet.Continued by: Bombay (India : State). Irrigation administration report.1899/1900-1928/29 include report for Sind, later published separetely as Sind (Pakistan). Public Works Dept.
Bombay (India : State). Public Works Department., Bombay (India : State). Public Works Department. Irrigation works, accounts and financial statements., Bombay (India : State). Public Works Department. Administration report of irrigation works.   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Community college in Canada : present status, future prospects /

, 1971
La couv. porte en outre: Report of the proceedings of the first Annual Banff Leadership Conference on College Administration, Banff, Alberta, June 17-19 ...
Bryce, Robert, Annual Banff Leadership Conference on College Administration (1st : 1970 : Banff, Alberta)   +1 more
core   +1 more source

Administration. Journal of the Institute of Public Administration of Ireland. 1980. Vol 28. No 4.

, 1980
Administration is published four times a year. It is the journal of the Institute of Public Administration Ireland. The views expressed in it are the views of the contributors, and not necessarily those of the Institute.
Litton, Frank, Institute of Public Administration (IPA)   +1 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Scientometrics Analysis of Research Studies on 43 Years of Leadership in Online Education

Journal of Learning for Development
Leadership in online education involves strategically managing digital learning environments to ensure effective instruction and engagement. This research aims to identify the publication trends and highlight trending research topics and scientific ...
Amir Karimi, Saibal Kumar Saha
doaj   +1 more source