Results 121 to 130 of about 4,141,685 (285)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Judicial Review of European Administrative Procedure [PDF]

open access: yes, 2004
Schwarze examines the requirements set down in the case law of the Court of Justice and the Court of First Instance that serve to guarantee a fair and impartial administrative process.
Schwarze, Jurgen
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Beliefs Of International And Domestic Foreign Language Teachers [PDF]

open access: yesJournal of the National Council of Less Commonly Taught Languages, 2011
In response to the shortage of foreign language (L2) teachers in the United States, many school districts employ individuals from other countries. Despite the benefits offered by such teachers, there is growing concern that they may not be adequately ...
Scott Kissau, Maria Yon, Bob Algozzine
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Administrative Transaction Data [PDF]

open access: yes
The value of administrative transaction data, such as financial transactions, credit card purchases, telephone calls, and retail store scanning data, to study social behaviour has long been recognised.
Julia Lane
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Percepción de la justicia organizacional de los empleados de la Universidad Técnica de Machala

open access: yesCiencia UNEMI, 2017
Organizational justice entails understanding how the employees of a company appreciate the decision-making of managers in the management of a company.
Quezada-Abad, César
doaj  

Understanding Foundation Expenses: Focus on Illinois [PDF]

open access: yes, 2013
Understanding Foundation Expenses: Focus on Illinois defines and delineates charitable (programrelated) administrative and operating expenses, which are those that count toward a foundation's payout requirement.
Loren Renz
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy