Results 61 to 70 of about 1,174,099 (265)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Fiscal year 2004-; Title from cover of 2004 PDF document (viewed July 18, 2005)
Ohio. Department of Administrative Services.
core +1 more source
Other title: DAS-ITS-2100-01-B Password Standard for Non-Organizational Users
, 2017 "Original Standard"--Page 4.; "Effective date: 07/12/2017."; Standard number: DAS-ITS-2100-01-B.; Includes bibliographical references.The purpose of this standard is to provide non-organizational user password requirements to Ohio Department of ...
Ohio. Department of Administrative Services +1 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Other title: DAS-ITS-2100-01-A Password Standard for Organizational Users
, 2017 "Original Standard"--Page 5.; "Effective date: 07/12/2017."; Standard number: DAS-ITS-2100-01-A.; Includes bibliographical references.The purpose of this standard is to provide organizational user password requirements to Ohio Department of ...
Ohio. Department of Administrative Services +1 more
core
Other title: Audit and Accountability Policy 2100-12
, 2020 At head of title: DAS policy; "Effective date: 12/22/2017."; Policy number: 2100-12; "Revision history: 12/22/2017, Original Policy; 12/04/2018, Conducted scheduled maintenance review, no changes were made to the policy as a result; 02/26/2020, Updated ...
Ohio. Department of Administrative Services
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Other title: System Maintenance Policy 2100-18
, 2020 [06/10/2020 update]; At head of title: DAS Policy; "Effective date: 12/21/2018."; Policy number: 2100-18; "Revision history: 12/21/2018, Original Policy; 06/10/2020, Updated the policy template..."--Page 7; Includes bibliographical referencesThe purpose ...
Ohio. Department of Administrative Services
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Other title: Data classification policy 2100-04
, 2020 [06/10/2020 update]; At head of title: DAS Policy; "Effective: 12/21/2018."; IT policy number: 2100-04; "Revision history: 12/01/2009, New policy for DAS, replaces OIT policy dated 11/02/07; 12/05/2012, Policy reissued under Director Robert Blair; 12/21/
Ohio. Department of Administrative Services
core