Results 41 to 50 of about 129,865 (246)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Administrative Acts Completely Removed from the Control of the Legality of the Administrative Contentious Courts

Journal of Danubian Studies and Research, 2022
With the appearance and establishment of the administrative contentious, the issue of the existence of an absolute right of control of the courts over administrative acts arose.
Maria Cristiana Ieremie
doaj  

TINJAUAN YURIDIS TERHADAP UNDANG-UNDANG TENTANG PERADILAN TATA USAHA NEGARA

Masalah-Masalah Hukum, 2011
As a Constitutional State, there should be Administrative Tribunal with tasks to protect human nghts of citizenship in administration law. In Indonesia the Administrative Tribunal were found by Act Number 5 year 1986, and it has been change two times ...
Aju Putrijanti
doaj   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

REASONS WHY THE ADMINISTRATIVE ACT CAN OVERRULE IN ADMINISTRATIVE DISPUTES

Zbornik Radova Pravnog Fakulteta u Splitu, 2008
By means of administrative dispute resolution, illegal public law activity, upon the issue of administrative acts, is sanctioned and corrected. This contributes to the establishment of legality and rule of law.
Snježana Pehar
doaj  

Guaranteeism in Administrative Acts

International Journal of Law and Public Administration, 2018
Under the reform of article 1 of the Federal Constitution (June 10, 2011), all government authorities have the obligation to respect human rights. The main inquiry of this essay is whether the Executive can, ex officio, revoke administrative acts for violations of human rights or stop enforcing a law it deems unconstitutional.
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Effectiveness Of Administrative Review In Indonesia’S Administrative Court System

Prophetic Law Review, 2019
This research aims to describe the use of administrative review in Indonesia. There are two rules of administrative review: administrative review according to Act Number 5 Year 1986 on State Administrative Judicial Action, and administrative review ...
Umar Dani
doaj   +1 more source