Endangered Species Act Innovations in the Post-Babbittonian Era—Are There Any? [PDF]
One of the mysteries of environmental policy in the Bush Administration will be how and why it squandered an opportunity to continue market-based administrative reforms of the Endangered Species Act begun, ironically, in the Clinton Administration under ...
Ruhl, J. B.
core +3 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Effectiveness Of Administrative Review In Indonesia’S Administrative Court System
This research aims to describe the use of administrative review in Indonesia. There are two rules of administrative review: administrative review according to Act Number 5 Year 1986 on State Administrative Judicial Action, and administrative review ...
Umar Dani
doaj +1 more source
The impact of the 2006-07 HE finance reforms on HE participation (BIS research paper no.13) [PDF]
"This report examines the effects of the package of reforms introduced by the Higher Education Act in 2006-07 on HE participation, using administrative data on all state school students in England, linked to HE records from all UK universities.
Crawford, Claire, Dearden, Lorraine
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The West German Administrative Procedure Act: A Study in Administrative Decision Making [PDF]
This Article examines the West German Administrative Procedure Act ( VwVfG ), which forms an essential element in the German model of administrative decision-making and provides valuable insight into the nature of administrative decision-making in ...
Eberle, Edward J.
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Building Consensus and Partnerships for Implementing the MAP-21 Section 5310 Program in California, MTI Report WP 12-25 [PDF]
The Moving Ahead for Progress in the 21st Century Act (MAP-21)—the legislation that currently provides funding for federal transportation—allows metropolitan planning organizations (MPOs) or eligible large, urbanized area (UZA) agencies to assume ...
Appleyard, Bruce, Ferrell, Christopher
core +1 more source
Does practice make perfect? Debate about principles versus practice in New Zealand local government planning [PDF]
Legislation and practice are two arms of public policy planning. Legislation empowers or enables; practice is the articulation and implementation of legislative principle.
Jay, Grace Mairi M.
core +2 more sources
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

