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Renascence of the administrative jurisdiction in Hungary

open access: yesBratislava Law Review, 2019
The administrative jurisdiction is one of the guarantees of the civil legal security. However, a state has to „grow up” to this as to every legal guaranties.
Edit Horváth
doaj   +1 more source

The Process of Evidencing (Offer of Proof) at Administrative Procedure [PDF]

open access: yes, 2012
The investigatory procedure carried out by an administrative organ during administrative proceedings is indispensable. There is no doubt that “lex specialis”, in several cases, tend to detail this process, however, it needs a “lex generalis” act which ...
Gërxhi, Julejda, Vokopola, Alma
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Legal Nature of Tax Cases in Turkish Law

open access: yesInternational Journal of Public Finance, 2020
Tax, as a concept, is money received from individuals based on public power. With the event that causes the tax, a tax liability arises on the taxpayer, and it is possible to collect a certain amount by using public power by the administration.
Onur Kaplan
doaj   +1 more source

Reforming the Administrative Procedure Act: Democracy Index Rulemaking [PDF]

open access: yes, 2005
This Essay argues that the current regime of administrative law should be changed by creating legal incentives for agencies to involve the public in the rulemaking process via democracy index rulemaking.
Fontana, David
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Administrative act: Concept and types [PDF]

open access: yesGlasnik Advokatske komore Vojvodine, 2010
The concept of administrative act is defined both in a theory and legislature. Based on that, we may say that administrative acts include general and individual legal acts passed by the administration, and on the other hand material acts carried out by the administration while performing powers vested in administration.
openaire   +1 more source

Does practice make perfect? Debate about principles versus practice in New Zealand local government planning [PDF]

open access: yes, 1999
Legislation and practice are two arms of public policy planning. Legislation empowers or enables; practice is the articulation and implementation of legislative principle.
Jay, Grace Mairi M.
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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