Results 61 to 70 of about 39,627 (302)
Regulation of economic activity is ubiquitous around the world, yet standard theories predict it should be rather uncommon. I argue that the ubiquity of regulation is explained not so much by the failure of markets, or by asymmetric information, as by ...
Andrei Shleifer
core +2 more sources
About subjects of administrative and legal relations in migration sphere
The article considers a classification of subjects of administrative legal relations in the migration sphere. In a chain of reasoning it is noted that there is a division on collective and individual in the subjects of legal relationship.
Sazonova Oxana Alexandrovna
doaj
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa +10 more
wiley +1 more source
A new system and legal regulation of administrative punishment in the Czech Republic [PDF]
This paper focuses on the new legal regulation that came into effect on 1.07.2017. This represents a relatively new approach to punishment realized by the administrative bodies.
Potěšil Lukáš, Potěšil, Lukáš
core +1 more source
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Topical Issues of Parental Administrative Liability for Neglect of Juveniles
The author analyzes legal regulation of administrative liability of parents or other legal representatives who are responsible for the juveniles and suggests innovations to improve legal regulation of these relations.
Svetlana L. Banshchikova
doaj +1 more source
THE SUBJECTS OF ADMINISTRATIVE AND LEGAL REGULATION OF MEDIATION
The article is devoted to the study of the subject composition of the administrative and legal regulation of mediation. The development of alternative ways of resolving disputes and conciliation procedures is one of the priority areas for improving the mechanism for protecting violated subjective rights.
openaire +2 more sources
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source

