Results 81 to 90 of about 39,627 (302)

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Evaluating administrative burdens through SCM: some indications from the Italian experience [PDF]

A methodology to measure administrative burdens, based on the Dutch Standard Cost Model (SCM), has been applied in a large number of European countries, coupled in most cases with the commitment to a reduction target.
Laura Cavallo, Giuseppe Coco, Mario Martelli   +2 more
core  

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

ECONOMIC AND LEGAL TRENDS OF EUROPEANIZATION OF THE ADMINISTRATIVE LAW OF UKRAINE

Фінансово-кредитна діяльність: проблеми теорії та практики
Today, it is appropriate to talk about cooperation between Ukraine and EU member states in matters that are functional for their legal systems. The first is the protection of the rights and freedoms of citizens; providing asylum to refugees from other ...
Oleksii Ostapenko, Mariia Blikhar, Iryna Khomyshyn, Leonid Ostapenko, Zoryana Dobosh, Ulyana Bek   +5 more
doaj   +1 more source

Administrative process as a kind of legal process: Modern problems of understanding and normative-legal regulation

, 2018
The article is devoted to the research of the phenomenon of the administrative process with the aim of developing its updated concept, which corresponds to the current state of the legal system of the Russian Federation, taking into account the recent ...
Zelentsov A.B., Kononov P.I., Stakhov A.I.   +2 more
core   +2 more sources

Migration policy: administrative and legal aspects

Studia Humanitatis, 2018
The article considers the features of migration policy of the Russian Federation. In a chain of reasoning the authors investigated specificity of administrative and legal regulation in the migratory sphere.
Sazonova Oxana Alexandrovna, Sazonova Nina Vasilevna   +1 more
doaj  

Ukraine administrative and legal regulation of education for persons with disability

Social Welfare: Interdisciplinary Approach, 2015
Education of people with disabilities as the object of administrative and legal regulation of public policy in Ukraine is analyzed in the article. It is stated that the society has passed a difficult path in its attitude to the people with disabilities -
Iryna Talanchuk
doaj   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

Notarial activity as an object of administrative and legal regulation

, 2010
Визначено види нотаріальної діяльності, які становлять об’єкт адміністративно-правового регулювання. Надано визначення механізму адміністративно-правового регулювання зазначеної діяльності.Определены виды нотариальной деятельности, которые составляют ...
Ільєва, Наталія Василівна, Ильева, Наталья Васильевна, Ilieva, Nataliia V.   +2 more
core   +1 more source

Labeling Quality or Quantity? The Differential Impact of Geographical Indications on Export Performance in Turkish Agri‐Food Products

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study investigates the impact of geographical indication (GI) certification on the export performance of Turkish agri‐food products by analyzing both trade volume and unit value dynamics. Drawing on monthly data from 2000 to 2024 across 22 GI‐certified products, the research employs product‐level regressions, fixed‐effects panel models ...
Ihlas Sovbetov, Muge Burcu Ozdemir
wiley   +1 more source