Results 141 to 150 of about 409,452 (309)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Administrative Control of Administrative Action [PDF]
California Law Review, 1969 openaire +1 more source
Administrative Bureaus with Standard Operating Procedures [PDF]
We investigate the terms of exchange between the legislative branch of the government and an administrative bureau with standard operating procedures. An administrative bureau is a not-for-profit public organisation responsible for the production of a ...
Miltos Makris
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Legal considerations of administrative control
, 2020 Fișierul atașat conține: Rezumat, Abstract, Cuprins, Introducere, Bibliografie.Structura tezei. Introducere, 4 capitole, concluzii generale și recomandări, bibliografie din 102 de titluri, 89 de pagini de text de bază. Actualitatea și impоrtanța temei
BOLBOȘENCO, Mariana
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
The Control of Public Administration
European Journal of Social Sciences, 2019 Public administration in Kosovo is in a development phase and it is being built under new circumstances which derived from the international civil administration. In this regard it is also ready to undergo under various forms of the control and supervision.
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Finding Aid for Assistant Chancellor for Administrative Services Administrative Subject Files, 1923-
, 1923 In the early history of Stout, the Business Manager had responsibility for all business affairs of the institution. As Stout grew, the business responsibilities also grew dramatically in complexity.
Assistant Chancellor for Administrative Services
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source