Results 121 to 130 of about 409,452 (309)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Internal administrative control [PDF]

open access: yes, 2017
El control interno es parte esencial para el direccionamiento de toda actividad económica ya que al paso de los años los criterios de evaluación han aumentado, este tiempo en que se daba el escenario de ser juez y parte ha quedado atrás y con ello ...
Barrera Romero, Luis Eduardo
core   +1 more source

Wartime Civil Control Administration administrative order #6

open access: yes, 1942
An administrative order that released information about press and radio announcements from W. C. C. A. entities. Certain information, such as evacuation orders and departure schedules, could only be issued from W. C. C. A. headquarters. Satellite offices
Bendetsen, Karl R.: author; Wartime Civil Control Administration: author
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Reported effectiveness of COVID-19 monovalent booster vaccines and hybrid immunity against mild and severe Omicron disease in adults: A systematic review and meta-regression analysis

open access: yesVaccine: X
Background: Waning of COVID-19 vaccine efficacy/effectiveness (VE) has been observed across settings and epidemiological contexts. We conducted a systematic review of COVID-19 VE studies and performed a meta-regression analysis to improve understanding ...
Joshua Nealon   +4 more
doaj   +1 more source

The Administrative Control of Diphtheria [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1925
openaire   +2 more sources

Control of Housing Administration

open access: yesLaw and Contemporary Problems, 1934
In any discussion of the housing problem it is necessary that we first determine just what we are going to discuss and that we define some of the terms to be used. Since the housing problem under consideration at the present time involves "lowcost housing" or housing for "low-wage earners," it is essential that we determine what we mean by these terms.
openaire   +2 more sources

Home - About - Disclaimer - Privacy