Results 61 to 70 of about 2,406,234 (305)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Measuring inequality and dependences between income sources with administrative data and survey data [PDF]
Producción CientíficaThis paper aims at analyzing the effects of changing from survey to administrative data on inequality and its structure. Taking advantage of the Spanish Survey on Income and Living Conditions (ECV) that continued asking households ...
Ayala, Luis +2 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Involving the public in transforming the data landscape in Scotland
International Journal of Population Data ScienceObjective In 2023 a public panel around public sector data use in Scotland was refreshed. The aim was to have a panel not only feedback on individual research projects but also the broader systems and processes of the data landscape in Scotland – from ...
Katie Oldfield, Harriet Baird
doaj +1 more source
How do you interpret a billion primary care records?
International Journal of Population Data Science, 2017 Background Research into General Practitioner (GP) records is relatively straightforward when it comes to establishing the prescribing of a particular drug or a specific disease group, but what if you want to use it to make more general inferences about ...
Martin Heaven +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Global socioeconomic inequalities in vaccination coverage, supply, and confidence
npj VaccinesSustainable Development Goal (SDG) adopted in 2015 aim to reduce inequalities and achieve universal health coverage, including access to essential vaccines for all.
Qiang Wang +4 more
doaj +1 more source
Housing policy researchers studying the intersection of housing and disability must understand the relative strengths and limitations of the various types of administrative and survey data that can be used to identify persons with disabilities.
Brucker, Debra L., Helms, Veronica
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source