Results 31 to 40 of about 2,175,383 (293)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mimar Sinan Fine Arts University information package [PDF]
, 2019 Mimar Sinan Fine Arts University information ...
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Administrative penalties: Impact and alternatives
Journal of Economic and Financial Sciences, 2011 Administrative penalties are imposed in South Africa for a specified set of prohibited practices. These are typically the most egregious anti-competitive acts, and therefore the main purpose of administrative penalties is to act as a deterrent, both to ...
Jason Aproskie, Sha’ista Goga
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Employing historical events in television drama
الاكاديميDrama is from the ancient human arts, it appeared with the presence of the old man, as it was the means that he used to simulate the surrounding reality and even his Aristotle imagination to embody it in the form of rituals and dances expressed in a ...
Amal Taher Hassan, Ali Ismail Khalil
doaj +1 more source
Management of Revenue from Administrative Fines: Russian Practice and International Experience [PDF]
Финансовый журналThe article provides a comprehensive analysis of approaches to improving revenue management within the budgetary system of the Russian Federation, using the administration of revenues from administrative fines as a case study.
Vladimir V. Olkhovik
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Development and Evaluation of a Retrieval-Augmented Generation-Based Electronic Medical Record Chatbot System [PDF]
Healthcare Informatics ResearchObjectives This study aimed to develop and evaluate a retrieval-augmented generation (RAG)-based chatbot system designed to optimize hospital operations. By leveraging electronic medical record (EMR) manuals, the system seeks to streamline administrative
Namrye Son +5 more
doaj +1 more source