Results 101 to 110 of about 9,384 (260)

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

ADMINISTRATIVE AND LEGAL RESPONSIBILITY AS A MEANS OF ENSURING ENVIRONMENTAL LAW AND ORDER

Хабаршы. Заң сериясы
This article examines the institution of administrative and legal accountability for environmental violations in the context of upholding environmental law and order.
Р. Ережепқызы, Ж.А. Битабарова, С.Д. Бекишева, С.К. Есетова, Л.К. Садуакасова   +4 more
doaj  

Engineering Na‐Rich P2‐Type Layered Oxides Through Li/Ti Dual Doping for Oxygen Redox Activation and Superior Structural Stability

Advanced Energy Materials, EarlyView.
P2‐type sodium layered oxides have potential for high‐voltage operation but suffer from structural instability and capacity fading. This work demonstrates that synergistic Li and Ti co‐doping enhances sodium inventory, suppresses detrimental phase transitions, and activates reversible lattice oxygen redox.
Rishika Jakhar, Shrestha Ghosh, Adesh Rohan Mishra, Shristi Pradhan, Debalina Sarkar, Yuanlong Bill Zheng, Zengqing Zhuo, Tianyi Li, Lu Ma, Minghao Zhang, Shyue Ping Ong, Matthew Li, Leeann Sun, Prabhat Thapliyal, Jing Wang, Abhik Banerjee, Ying Shirley Meng   +16 more
wiley   +1 more source

Electrocatalytic Urea Waste Valorization via Water Electrolysis: Transition‐Metal Phosphides for Sustainable Hydrogen Production

Advanced Energy Materials, EarlyView.
This article provides a comprehensive analysis of transition metal phosphides (TMP) as electrocatalysts for urea‐assisted water electrolysis, highlighting the critical role of phosphorus engineering in modulating electronic structure, optimizing active sites, and enhancing catalytic durability.
Shivalingayya Gaddimath, Varsha Kashanner, Soumya Kulkarni, Vishal Sorathiya, Anitha Bamani, Rajveer Singh Rajaura, Mahaveer Kurkuri, Shambhulinga Aralekallu, Yogendra Kumar Mishra   +8 more
wiley   +1 more source

Multiscale Design of Anion Exchange Membrane‐Based Seawater Electrolysis for Sustainable Hydrogen Production

Advanced Energy Materials, EarlyView.
Direct seawater electrolysis using anion exchange membranes is emerging as a promising route for sustainable hydrogen production. This review summarizes multiscale design strategies from seawater chemistry and OER–ClER selectivity to catalysts, membranes, MEAs, cells, stacks, and system integration, providing a roadmap toward selective, durable, and ...
Chiho Kim, Geunhee Yuk, Jong‐Hyeok Park, Shin‐woo Myeong, Jun Seok Ha, Won Tae Hong, Jung Kyu Kim, Sung Mook Choi   +7 more
wiley   +1 more source

Design Principles of Electrocatalysts for Industrial‐Scale Water Electrolysis

Advanced Energy Materials, EarlyView.
This Review distills electrocatalyst design for industrial‐scale water electrolysis into integrated principles linking active‐site engineering, phase and lattice modulation, interfacial microenvironment regulation and mass‐transport control. By connecting catalyst families with HER/OER mechanisms and practical operating demands, it outlines pathways ...
Hong Tang, Cui Ce, John Wang
wiley   +1 more source

Fluorinated Methylammonium Cation Containing Perovskite Solar Cells With Over 25% Power Conversion Efficiency

Advanced Energy Materials, EarlyView.
Fluoromethylammonium iodide (FMAI) is prepared using a facile procedure through a simple nucleophilic reaction between fluoroiodomethane and ammonia in methanol and tested in n‐i‐p perovskite solar cells. FMA+ cation in combination with FA+ and Cs+ cations affords a power conversion efficiency close to 26% with a long‐term operational stability for ...
Justina Mikuciunaite, Bin Ding, Yuxuan Yang, Xiao‐Xin Gao, Vida Valipour, Yong Ding, Negar Ashari Astani, Jan Romano‐deGea, Lindsey E. K. Frederiksen, Farzaneh Fadaei Tirani, Vytautas Getautis, Yi Zhang, Mohammad Khaja Nazeeruddin, Kasparas Rakstys   +13 more
wiley   +1 more source

Keeping Pace or Falling Behind? The Depth of Latin American Trade Agreements

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This article examines whether Latin American countries are keeping pace with global trends in trade agreement depth or falling behind. Using 681 agreements (1970–2019), we develop the Depth Index of Trade Agreements (DITA) to weight provisions endogenously through factor analysis based on co‐occurrence patterns.
Raphael Gomes da Silva, Fernanda Aparecida Silva, Lia Nogueira   +2 more
wiley   +1 more source

Sanção administrativa e termo de compromisso como instrumentos de enforcement à disposição da CVM: uma análise à luz de seus efeitos

Revista de Direito Setorial e Regulatório
[Purpose] To identify the incentives that administrative sanctions and settlement agreements in sanctioning processes can create for aligning the behavior of regulated agents with the regulations governing the securities market.
Carolina Estarque
doaj