Results 71 to 80 of about 956,741 (318)

AI‐Driven Acceleration of Fluorescence Probe Discovery

open access: yesAdvanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang   +18 more
wiley   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

open access: yesAdvanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen   +22 more
wiley   +1 more source

Comparison of Provisions from Colorado's Blue Ribbon Commission for Health Care Reform and Federal Health Care Reform [PDF]

open access: yes, 2010
A new issue brief commissioned by The Colorado Trust, and authored by the two lead staff members of the Colorado's Blue Ribbon Commission on Healthcare Reform (the 208 Commission), Tracy L.
Sarah Schulte, Tracy L. Johnson
core  

Economic consequences of administrative penalties on violations by IPO sponsor representatives

open access: yesChina Journal of Accounting Studies, 2018
It is a crucial issue in the theory and practice of securities regulation, to improve regulation of securities institutions and avoid securities fraud. Using IPO sponsor supervision data by the China Securities Regulatory Commission (CSRC) for the period
Yang Yi   +3 more
semanticscholar   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Saving Disgorgement from Itself: SEC Enforcement After Kokesh v. SEC [PDF]

open access: yes, 2014
Disgorgement is under threat. In Kokesh v. SEC , the Supreme Court held that disgorgement—a routine remedy that allows the SEC to recoup ill-gotten gains from financial wrongdoers—is subject to a 5-year statute of limitations because it functions as a ...
Ahlskog, Stina, Karlsson, Elisabeth
core   +2 more sources

Pension-Induced Rigidities in the Labor Market for School Leaders [PDF]

open access: yes
Educators in public schools in the United States are typically enrolled in defined-benefit pension plans, which penalize across-plan mobility. We use administrative data from Missouri to examine how the mobility penalties affect the labor market for ...
Cory Koedel   +3 more
core   +3 more sources

LOSS (OF REVENUE) OF STATE WITHIN TAXATION CRIMES IN INDONESIA

open access: yesMimbar Hukum, 2018
The  difference of state’s tax loss amount between tax investigation, which has been completely declared by the Prosecutor, and judicial verdict can not be separated from the existence of the defendant’s right to propose  Witnesses/Experts, and or the ...
Henry Dianto Pardamean Sinaga
doaj   +1 more source

Who are Taxable?—Basic Problems in Definition Under the Illinois Retailers’ Occupation Tax Act [PDF]

open access: yes, 1941
Identification of non-linear systems is a challenge, due to the richness of both model structures and estimation approaches. As a case study, in this paper we test a number of methods on a data set collected from an electrical circuit at the Free ...
Iouditski, Anatoli   +3 more
core   +2 more sources

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

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