Results 81 to 90 of about 1,319,769 (311)

Dissertation council in the state scientific certification system: Organizational and management mechanisms of digital transformation

Управленец
Currently, there is a need to refine the underlying mechanisms of dissertation councils as key elements of the state scientific certification system in Russia.
Sergey I. Pakhomov, Elena A. Loginova, Oleg V. Kulyamin, Mikhail P. Petrov   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Administrative and Procedural Form as a Category of Administrative Procedure

Actual Problems of Russian Law, 2022
The paper describes the administrative-procedural forms of activity of public administration entities, shows their importance in the administrative process, identifies and characterizes their main features, and suggests their classification. The author describes the main approaches to the use of the concept of «procedural form» in legislation and law ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

COMPARATIVE ANALYSIS OF FORENSIC EXPERT ACTIVITY: AN ADMINISTRATIVE, CRIMINAL, CRIMINALISTIC, ECONOMIC APPROACH

Baltic Journal of Economic Studies, 2019
The article is devoted to the economic and legal comparative analysis of judicial expert activities. The issues concerning the problems of quality assurance of the expert activities, harmonization and convergence of the understanding of the possibilities
Oleksandr Khrystov, Vladyslav Lipynskyi
doaj   +1 more source

From Illegal to Legal: Estimating Previous Illegal Experience among New Legal Immigrants to the United States [PDF]

This paper develops a framework for estimating previous illegal experience among annual cohorts of new legal immigrants to the United States – using public-use administrative microdata alone, survey data alone, and the two jointly – and provides ...
Jasso, Guillermina, Massey, Douglas S., Rosenzweig, Mark R., Smith, James P.   +3 more
core  

Case Note: Transportation Law - Urban Mass Transportation Act - The Absence of Statutory Provisions Relating to Standing and Judicial Review Does Not Preclude a Claimant from Seeking Relief in Federal Court [PDF]

, 1977
This case note by Terry L. Barnich analyzes the Seventh Circuit\u27s decision in Bradford School Bus Transit, Inc. v. Chicago Transit Authority, 537 F.2d 943 (7th Cir. 1976), cert denied, 97 S. Ct. 797 (1977). The plaintiff, a private bus company, sought
Barnich, Terry L.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

ANALYSIS OF THE INVESTMENT CLIMATE OF DENMARK [PDF]

Êvropejsʹkij Vektor Ekonomìčnogo Rozvitku
The investment climate is a key factor for attracting capital, stimulating innovation and strengthening competitiveness. The purpose of the study is to analyze the current state of the investment environment in the country, assess its attractiveness for
Elvina Lymonova, Marina V. Filchenkova
doaj   +1 more source