Results 101 to 110 of about 251,089 (308)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Administrative Barriers to Foreign Investment in Developing Countries

, 2002
Recent international experience has shown that excessively complex administrative procedures, required to establish, and operate a business, discourage inflows of foreign direct investment. The authors present a
Morisset, Jacques, Lumenga Olivier Neso, Lumenga Neso, Olivier, Jacques Morisset   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

ACADEMIC OBJECTIVES AND ADMINISTRATIVE PROCEDURES

, 2020
KEAN UNIVERSITY ACADEMIC OBJECTIVES AND ADMINISTRATIVE PROCEDURES The following procedures have been compiled here to create a consistent and cogent document to ensure the delivery of efficient world-class academic services and opportunities to Kean ...
Kean University
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Key administrative procedures in the enforcement of intellectual property rights in the EU and Ukraine

Теорія і практика інтелектуальної власності
The article offers a doctrinal and comparative analysis of the instruments used to protect IP rights in the EU and Ukraine through administrative procedures. It argues that these procedures constitute the «first line» of preventive enforcement.
Sergiy Glotov
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Crab of Chuan-tzu. The Regulation of Italian Administrative Procedures in a Global and Comparative Perspective

, 2011
To expect a legislature, in any given legal order, to simultaneously enhance both participation and simplicity in administrative procedures, may appear as expecting a circle to be squared.
BATTINI S
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RETRACTED: DIGITALISATION OF ADMINISTRATIVE PROCEDURES IN THE FIELD OF ECONOMIC COMPETITION CONTROL: CHALLENGES AND OPPORTUNITIES FOR UKRAINE

Baltic Journal of Economic Studies
This article has been retracted. Please see the Baltija Publishing Policy on Article Withdrawal (http://baltijapublishing.lv/index.php/issue/policies_ethics).
Yan Braslavets
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Administrative procedures in the border police

, 2020
Ovim radom temeljitije će se ući u problematiku upravnih postupaka u graničnoj policiji. Upravno pravo je usmjereno na pravne norme koje čine organizaciju uprave, područje njena djelovanja, načine rada, nadzora i druga brojna područja koja ćemo pobliže ...
Knežević Miljanić, Marijana
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