Results 121 to 130 of about 1,319,769 (311)

Managed Care’s Crimea: Medical Necessity, Therapeutic Benefit, and the Goals of Administrative Process in Health Insurance [PDF]

open access: yes, 2003
This Essay explores the concept of medical necessity as it has evolved in the judicial and administrative oversight of managed care. The goals of the Essay are to illustrate the range of plausible rationales for establishing administrative procedures to ...
Sage, William M.
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Electronic administrative procedure

open access: yes, 2018
In Peru, as part of the implementation of electronic government, a process of incorporation of Information and Communication Technologies (ICTs) is being carried out so that citizens can relate to public administration entities. by electronic means to present writings, resources and complaints; make payments; receive notifications when ...
Patrón Bedoya, Pedro   +1 more
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

EXPLORING THE LEGALITY OF AI IN CUSTOMS PROCEDURES [PDF]

open access: yesChallenges of the Knowledge Society
This paper explores the complex interaction between AI and customs procedures, aiming to uncover the legal ramifications associated with the integration of AI technologies in this field.
Andrei-Alexandru STOICA   +1 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EU Services Directive - Design Approaches for Romania [PDF]

open access: yes
Modernizing public administration is the basis for implementation of the EU directive, and in order to ensure this successfully, collaborative procedures between administrative institutions and countries must be put in place and further developed.
Catalin Ionut SILVESTRU   +3 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Awarding academic titles as a public service: Optimization of administrative procedures and transition to a digital model

open access: yesУправленец
The transition to a digital model of providing the public service of conferring academic titles implies fundamental changes in this public institution, which are associated with both the need to make a technological map for digitizing the service and ...
Sergey I. Pakhomov   +2 more
doaj   +1 more source

Адміністративні процедури у публічній службі України [PDF]

open access: yes, 2010
Фоміч Г. В. Адміністративні процедури у публічній службі України : автореф. дис. ... канд. юрид. наук : 12.00.07 / Г. В. Фоміч; кер. роботи С. В. Ківалов; Нац. ун.-т "Одеська юридична академія". – Одеса, 2010.
Fomich, Anna V.   +2 more
core  

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