Results 111 to 120 of about 1,319,769 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The impact of cleansing procedures for overlaps on estimation results : evidence for German administrative data [PDF]

open access: yes
"Process-generated and administrative datasets have become increasingly important for labor market research over the past ten years. Major advantages of these data are large sample sizes as well as absence of retrospective gaps and unit non-responses ...
Scioch, Patrycja
core  

Why the New York State System for Obtaining a License to Carry a Concealed Weapon is Unconstitutional [PDF]

open access: yes, 1998
The New York State administrative system for obtaining a license to carry a concealed weapon violates the state constitution and the tenets of administrative law vital to a democratic society.
Novak, Suzanne
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Key administrative procedures in the enforcement of intellectual property rights in the EU and Ukraine

open access: yesТеорія і практика інтелектуальної власності
The article offers a doctrinal and comparative analysis of the instruments used to protect IP rights in the EU and Ukraine through administrative procedures. It argues that these procedures constitute the «first line» of preventive enforcement.
Sergiy Glotov
doaj   +1 more source

The Arbitration Profession in Transition: Preliminary Results From a Survey of the National Academy of Arbitrators [PDF]

open access: yes, 2000
[Excerpt} In recent years, there has been a dramatic increase in the arbitration and mediation of employment-related disputes. This increase has been part of a larger shift from reliance on litigation and agency resolution of disputes to the use of ...
Lipsky, David B   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

RETRACTED: DIGITALISATION OF ADMINISTRATIVE PROCEDURES IN THE FIELD OF ECONOMIC COMPETITION CONTROL: CHALLENGES AND OPPORTUNITIES FOR UKRAINE

open access: yesBaltic Journal of Economic Studies
This article has been retracted. Please see the Baltija Publishing Policy on Article Withdrawal (http://baltijapublishing.lv/index.php/issue/policies_ethics).
Yan Braslavets
doaj   +1 more source

A Case Study of an Agency\u27s Three Family Preservation Contracts [PDF]

open access: yes, 2002
This article presents a case study of a nonprofit child welfare agency that delivered family preservation services under three different purchase-of-service (POS) contracts.
Ezell, Mark
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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