Results 101 to 110 of about 1,905,858 (334)
Currently, almost one in five adult Poles invests in cryptocurrencies. Given the already relatively large and still growing number of investors in this group, it can be expected that some of them will also be liable under the provisions on ...
Joanna Radwanowicz-Wanczewska
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Objective. The article is devoted to the analysis of information support of administrative and jurisdictional activities in relation to proceedings on administrative offenses which are within the competence of the State Border Guard Service of Ukraine ...
Kushnir I.
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Mediacja jako sposób dochodzenia praw w postępowaniu administracyjnym i sądowoadministracyjnym
The article presents mediation as the basic method of alternative dispute resolution (the so-called ADR), used to resolve conflicts in administrative and judicial-administrative proceedings, and analyses legal regulations regarding mediation in ...
Katarzyna Kułak-Krzysiak
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Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Federal Law 451-FZ has introduced new institutions represented by transformational procedures to the norms of the Civil Procedure Code of the Russian Federation and the Code of Administrative Procedure of the Russian Federation.
Natalia G. Galkovskaya
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Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On enforcement proceedings, administrative process and enforcement [PDF]
Салманова О.Ю. Про виконавче провадження, адміністративний процес і правозастосування / Салманова О.Ю. // Науковий вісник Херсонського державного університету. Серія: Юридичні науки. − 2015. − Вип. 3, Ч.2. Т. 1. − С.
ORCID: http://orcid.org/0000-0002-6376-1160 +2 more
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