Results 81 to 90 of about 11,257,904 (257)

Estopping the Commissioner of Taxation to ensure administrative accountability

open access: yes, 2016
Notwithstanding that no conduct on the part of the Commissioner of Taxation can be raised as an estoppel against the operation of the Tax Act, nevertheless, this paper argues that administrative estoppel is both appropriate and available to ensure the ...
Azzi, John (R16318)
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Europeanization or Curricular Harmonization in the Area of Administrative Sciences (Follow-Up of Bologna Process): Comparative Analysis and Empirical Research [PDF]

open access: yes
The paper aims a comparative analysis of curricula for Bachelor studies in the area of administrative sciences. The objectives of research focused on elaboration of a set of indicators, based on the curricular contents of the programmes from the first ...
Matei, Lucica
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Introduzione al tema: international administrative law and global administrative law

open access: yes, 2019
La relazione introduttiva ha avuto ad oggetto l'emergente dottrina del "Global administrative law" (Kingsbury, Cassese) in connessione con gli studi tradizionali in tema di "international administrative law ...
luigi ferrara
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Fundamentals of the administrative decentralization process [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series, 2017
Public administration, as an activity carried out by the administrative authorities, can be achieved through several forms of organization. In this sense, centralization, deconcentration and decentralization, together with its corollary, local autonomy ...
Mihaela Lupăncescu
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Codification of Norms on Judicial Consideration of Cases on Administrative Offenses: Experience of 16 Neighboring Countries

open access: yesСибирское юридическое обозрение
The article discusses the evolution of legislation concerning the judicial review of administrative offense cases across post-Soviet countries. It concludes that the Fundamentals of the Legislation of the USSR and the Union Republics on Administrative ...
S. V. Schepalov
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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