Results 91 to 100 of about 22,243,549 (342)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Administrative Regulations: Concept, Features, Problems of a Legal Regulation
Теоретическая и прикладная юриспруденцияThe article analyzes a variety of normative legal acts, which is relatively new for the Russian legal system — administrative regulations. Signs that distinguish administrative regulations from other departmental regulatory legal acts are identified. The
V. A. Lushnikova
doaj +1 more source
Fixing Advising: A Model for Faculty Advising [PDF]
, 2014 This paper addresses mandates to fix the advising process with a focus on faculty advising systems. Measures of student success and satisfaction, administrative issues, and faculty concerns are among the many factors discussed.
Allen, Charlotte +2 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
МЕЖЛИЧНОСТНАЯ КОММУНИКАЦИЯ – СТРУКТУРНЫЙ КОМПОНЕНТ УПРАВЛЕНЧЕСКОГО ПРОЦЕССА
Фінансово-кредитна діяльність: проблеми теорії та практики, 2014 Настоящая статья посвящена рассмотрению феномена «межличностная коммуникация», его влияния как структурного компонента на эффективность управленческой интеракции в контексте организационных взаимодействий.
O. M. Кульбашна
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Corporate Governance in Accredited Public Higher Education Institutions
Revista Científica General José María CórdovaThe specialized literature shows that corporate governance in accredited public higher education institutions is polysemic. This research will structure an integral corporate governance model for official higher education.
Fabio Mejía-Zambrano +2 more
doaj +1 more source
Barcoding and ILS Migration from Start to Finish: A Case Study
, 2018 This practice-oriented article outlines one institution’s process of implementing both electronic checkout and a new integrated library system (ILS) for an academic library of 187,000 physical items.
Arjona, Beth
core +1 more source
Judicialization of Administrative Law: The Trial-Type Hearing and the Changing Status of the Hearing Officer [PDF]
, 1977 The judicialization of the administrative process, a phenomenon largely taken for granted by both lawyers and the general public in contemporary America, is probably one of the most mysterious, yet significant, features of American government.
Davis, Frederick
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source