Results 111 to 120 of about 11,257,904 (257)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Other title: DAS-ITS-700-03 Encrypted USB Drive Standard

, 2020
[2020 update]; At head of title: DAS Standard; "EFFECTIVE DATE: 06/28/2017.;" "Revision history: 06/28/2017, original standard; 12/04/2018, updated the exception request language to align with the current procedure; 05/27/2020, Updated standard template ...
Ohio. Department of Administrative Services
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Other title: Multifactor Authentication Policy 2100-14

, 2020
[2020 update]; At head of title: DAS Policy; "Effective date: 12/22/2017."; "Revision history: 12/22/2017, Original Policy; 11/26/2018, Updated the exception request language to align with the current procedure; 02/26/2020, Updated the policy template to
Ohio. Department of Administrative Services
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Ohio Department of Administrative Services ... annual report

, 2004
Fiscal year 2004-; Title from cover of 2004 PDF document (viewed July 18, 2005).; Harvested from the web on 7/18 ...
Ohio Dept. of Administrative Services, Ohio. Dept. of Administrative Services.   +1 more
core  

Other title: Access Controls Policy 2100-11

, 2020
[2020 update]; At head of title: DAS Policy; "Effective date: 10/10/2017."; Revision history: "10/10/2017: Original Policy; 8/17/2018, Reviewed policy and moved disabled account and self-service mechanism requirements to the now published DAS IT ...
Ohio. Department of Administrative Services
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Crafting the Future: How Starhaus Innovations Advance Sustainable Governance and Align with UN SDGs

Transylvanian Review of Administrative Sciences
The Fast-Moving Consumer Goods (FMCG) sec­tor is a major source of greenhouse gas emissions and plastic waste, underscoring the urgency of sys­temic innovation in production and consumption. STARHAUS project, funded by the European Union, addresses this
Chandana Ratnayake, Raluca Ioana Antonie, Cristina Hințea, Maria Forna   +3 more
doaj   +1 more source

The Administrative Process

Duke Law Journal, 1975
Charles R. McManis, Glen O. Robinson, Ernest Gellhorn   +2 more
openaire   +1 more source