Results 121 to 130 of about 22,243,549 (342)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Organisational Impact of Implementing Integrated IS in HE institutions: a case study from a UK University [PDF]
, 2014 This paper explores the implementation process of integrated Information Systems (IS) in Higher Education (HE) institutions. This is achieved through the analysis of a HE institution’s strategy during the implementation process of the integrated IS and ...
Skoumpopoulou, Dimitra, Waring, Teresa
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
JurisprudencijaIn Lithuania, the legality of administrative decisions made by the state and its institutions is controlled by administrative courts, and the administrative process is regulated by the Law on Administrative Proceedings.
Linas Meškys
doaj
Foreign experience of public administration in the context of the economic equilibrium of synthetic economic crisis [PDF]
, 2017 This article identify catalysts of synthetic economic crisis. These catalysts are the subject of transnational corporations, international financial, trade organizations, regional integration groupings.
A. Gladchenko, S. Sardak, V. Dzhyndzhoian +1 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Decentralization Process of Rural Development Policy in Greece [PDF]
The decentralization process of national administrative systems, the continuous evolution of structural policies in the EU and the increasing reinforcement of the second Pillar of the Common Agricultural Policy, create an entirely new setting in the ...
Pavlos Karanikolas, Sofia Hatzipanteli
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Crafting the Future: How Starhaus Innovations Advance Sustainable Governance and Align with UN SDGs
Transylvanian Review of Administrative SciencesThe Fast-Moving Consumer Goods (FMCG) sector is a major source of greenhouse gas emissions and plastic waste, underscoring the urgency of systemic innovation in production and consumption.
Chandana Ratnayake +3 more
doaj +1 more source
The administrative process for recognition and compensation for occupational diseases in Korea. [PDF]
J Korean Med Sci, 2014 Kwon SC, Kim HR, Kwon YJ.
europepmc +1 more source