Results 131 to 140 of about 11,257,904 (257)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Annual report (2004 : Online); Other title: Ohio Department of Administrative Services ... annual report

open access: yes
Fiscal year 2004-; Title from cover of 2004 PDF document (viewed July 18, 2005)
Ohio. Department of Administrative Services.
core   +1 more source

Other title: DAS-ITS-2100-01-A Password Standard for Organizational Users

open access: yes, 2017
"Original Standard"--Page 5.; "Effective date: 07/12/2017."; Standard number: DAS-ITS-2100-01-A.; Includes bibliographical references.The purpose of this standard is to provide organizational user password requirements to Ohio Department of ...
Ohio. Department of Administrative Services   +1 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Other title: Data classification policy 2100-04

open access: yes, 2020
[06/10/2020 update]; At head of title: DAS Policy; "Effective: 12/21/2018."; IT policy number: 2100-04; "Revision history: 12/01/2009, New policy for DAS, replaces OIT policy dated 11/02/07; 12/05/2012, Policy reissued under Director Robert Blair; 12/21/
Ohio. Department of Administrative Services
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

ADMINISTRATIVE PROCEEDINGS AS A COMPONENT OF THE ADMINISTRATIVE PROCESS

open access: yesScientific Journal of Public and Private Law, 2023
openaire   +1 more source

Data Processing in University Administration [PDF]

open access: yesThe Computer Journal, 1960
P. F. Windley   +2 more
openaire   +1 more source

Other title: System Maintenance Policy 2100-18

open access: yes, 2020
[06/10/2020 update]; At head of title: DAS Policy; "Effective date: 12/21/2018."; Policy number: 2100-18; "Revision history: 12/21/2018, Original Policy; 06/10/2020, Updated the policy template..."--Page 7; Includes bibliographical referencesThe purpose ...
Ohio. Department of Administrative Services
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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