Results 51 to 60 of about 1,963,455 (292)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Administrative Responsibility for Offenses in Economic Areas [PDF]
, 2020 Relations in economic areas is a special sphere of social relations, which is associated with the phenomenon of ownership and which are regulated by civil, budget, tax, customs legislation and others.
M. N. Kobzar-Frolova
core
Promising ways impoving legislation on administrative responsibility [PDF]
, 2015 Стаття присвячена проблемі вдосконалення законодавства про адміністративну відповідальність. Розглянуто сутність і зміст таких питань: стан законодавства України про адміністративну відповідальність, особливості адміністративно-правового регулювання ...
Лозинський, Ю.Р.
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Правоприменение, 2018 The subject of the paper is constituent entities’ powers in federative state concerning the establishment of the administrative responsibility for breach regional and municipal rules.The purpose of the paper is to justify the need for new approaches to ...
O. Kozhevnikov
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
MISUSE OF LAND: SOME CHALLENGES OF ADMINISTRATIVE RESPONSIBILITY
Гуманитарные и юридические исследования, 2021 Administrative responsibility is the most common type of legal liability applied for violations in the field of land legislation; its implementation in practice aims to maintain the proper land law and order in the state and thereby ensure the rational ...
Mariya Verbitskaya, Tatiana Svetlichnaya
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Сибирское юридическое обозрение, 2017 The effectiveness of bringing to administrative responsibility for providing financial support to legal entities in the Russian Federation is discussed. The analysis of Russian financial monitoring's (Rusfinmonitoring) work on bringing legal entities to ...
Viktor V. Yunusov
doaj +1 more source