Results 101 to 110 of about 166,876 (291)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Revista Vasca de Administración Pública, 2018 The Act 40/2015 of the legal regime of the Public Sector has introduced a new rule on the calculation of the limitation period to be applied to sanctions in cases where hierarchichal appeal filed against them had been rejected by administrative silence ...
Carmen Chinchilla Marín
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Tindak Pidana Korupsi (Dugaan Penyalahgunaan Wewenang) Pejabat Publik (Perspektif Undang-undang Nomor 30 Tahun 2014 Tentang Administrasi Pemerintahan) [PDF]
, 2015 Allegation of abuse of authority that committed by public officials is an object to should be examined with the specialty principle (specialialiteit beginsel), because the deviation from this principle would impact to abuse of authority (detournement de
Fathuddin, F. (Fathuddin)
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Sanksi Administratif terhadap Ppat Atas Kelalaian Pengawasan Pembayaran Bphtb dalam Pembuatan Akta Peralihan Hak Atas Tanah [PDF]
, 2016 Government Regulation No. 37/1998 on PPAT (Official Empowered to Draw up Land Deeds) states that in the case of transferring of title on land and building, PPAT/Notary has the authority to draw up a certificate and validates the rights, and he also has ...
SITOMPUL, S. Y. (SRI)
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Enforcement of judgements in disputes over legality; study of practical case
Zbornik Radova Pravnog Fakulteta u Splitu, 2015 Although it is one of the fundamental characteristics of a state ruled by law, true and complete enforcement of administrative judgements which nullify certain administration acts has not always been guaranteed in France.
Jean-Michel Lemoyne de Forges
doaj
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source