Results 151 to 160 of about 6,990 (302)

Administrative Freezing of Capital Construction

open access: yes, 2015
The author estimates administrative freezing of capital construction as a type of punishment for violating laws in this sphere. The article provides the mechanism of freezing of capital construction as a serious alternative for fine ...
Kropacheva A. V., A. V. Kropacheva
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

La nature de l’interdiction temporaire de lieu : sanction administrative ou mesure de police administrative ?, note sous Cour constitutionnelle, 23 avril 2015, n° 44/2015

open access: yes, 2016
La loi du 24 juin 2013 relative aux sanctions administratives communales a fait l’objet de quatre recours en annulation devant la Cour constitutionnelle.
Andersen, Robert
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Administrative fines

open access: yes, 2008
Günlük yaşamımızda önemli bir yere sahip olan idarenin parasal yaptırımları, son dönemde özellikle Ceza Hukuku'nda yaşanan gelişmeler nedeniyle öne çıkmıştır.
Kütük, Levent
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Anticompetitive practices sanction : a critical approach

open access: yes, 2015
Les pratiques anticoncurrentielles se sont multipliées d’une façon préoccupante. Face à ce risque, le législateur national et celui de l’Union européenne ont opté pour un système répressif basé sur une diversité des sanctions.
Benziouche, Sarah
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Sanção administrativa e termo de compromisso como instrumentos de enforcement à disposição da CVM: uma análise à luz de seus efeitos

open access: yesRevista de Direito Setorial e Regulatório
[Purpose] To identify the incentives that administrative sanctions and settlement agreements in sanctioning processes can create for aligning the behavior of regulated agents with the regulations governing the securities market.
Carolina Estarque
doaj  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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