Results 51 to 60 of about 263,460 (307)
BRIEF CONSIDERATIONS REGARDING THE PUBLIC SERVANTS ADMINISTRATIVE-DISCIPLINARY LIABILITY [PDF]
Challenges of the Knowledge Society, 2021 The recent legal changes in the field of administrative law have led to a unitary regulation of many judicial institutions, by means of codification. However, in the Administrative Code, we can notice an insufficient allocation of regulation space for ...
Elena Emilia ȘTEFAN
doaj
The enforcement of environmental law: civil or criminal penalties? [PDF]
, 2005 In the United Kingdom, regulatory bodies have traditionally relied on the use of the criminal law to protect the environment. Although the officials employed by these agencies may have regarded it as the ‘last resort’, prosecution – or at least the ...
Watson, Michael
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
, 2002 On 1st December 2001, the Financial Services and Markets Act 2000 (‘FSMA’) came into force. One of its most controversial sections is Part VIII which gives the Financial Services Authority (‘FSA’) the power to impose civil penalties for market abuse ...
Alcock, A
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Khizanah al-Hikmah, 2018 Tujuan penelitian ini adalah untuk mengetahui hubungan pesan penagihan koleksi melalui media sosial dengan sikap pemustaka terhadap sanksi administratif perpustakaan, dengan menguji hubungan intensitas, isi pesan, dan daya tarik pesan dengan penghindaran
Aulia Asmayanti +2 more
doaj +1 more source
Work incentives?: ex post effects of unemployment insurance sanctions ; evidence from West Germany [PDF]
, 2008 Unemployment insurance (UI) sanctions in the form of benefit reductions are intended to set disincentives for UI recipients to stay unemployed. Empirical evidence about the effects of UI sanctions in Germany is sparse.
Hofmann, Barbara
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source