Results 101 to 110 of about 6,940 (275)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
ADMINISTRATIVE SILENCE WITHIN THE THEORY AND PRACTICE IN SLOVENIA
, 2011 U radu se kritičkom analizom izmjena regulacije i provedbe Zakona o općem upravnom postupku (ZUP) razmatraju teorijski i praktični aspekti instituta šutnje uprave u Republici Sloveniji.
Kovač, Polonca, Polonca Kovač
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Justicia, 2008 Para brindarles a los particulares medios idóneos para su desenvolvimiento en la sociedad, el constituyente a través del artículo 23 de la Carta Política actual, elevado a derecho fundamental, le otorga a las personas la posibilidad de impulsar la ...
Fabio César Amorocho Mart +1 more
doaj
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
The state of fundamental legal rights in Australia [PDF]
, 2014 Executive summary: This report demonstrates that a serious problem exists with respect to fundamental legal rights in Australian law. Our research has focussed on the extent to which four such fundamental legal rights are abrogated in current acts of the
Simon Breheny
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The applicability of the Institute of Administrative Science in the Macedonian legisletion [PDF]
, 2016 In the Republic of Macedonia "administrative silence" means a legal presumption according to which on the occasion of a request submitted by the party to the state authority, the authority does not respond to the request in the legally prescribed period ...
Denkova, Jadranka, Angelovski, Andrej
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, 2022 Dissertação de Mestrado em Direito apresentada à Faculdade de DireitoApesar de ser uma matéria há muito tempo estudada no Direito Administrativo, o silêncio administrativo ganhou um novo significado em um contexto de sociedade pós-moderna, principalmente,
Machado, Anna Paula Matsuoka Pandim Barbosa
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La Administración no puede beneficiarse de su silencio
Revista Vasca de Administración Pública, 2010 If the Administration provokes legal uncertainty by means of a clearly illegal conduct, it cannot take advantage from that uncertainty by pretending to benefit vis-à-vis those that suffered the uncertainty generated from its silence.
Iñaki Agirreazkuenaga Zigorraga
doaj +1 more source