Results 61 to 70 of about 6,940 (275)

Simplificación procedimental y optimización del funcionamiento de la Administración francesa

open access: yesRevista Vasca de Administración Pública, 2014
This paper presents Act 2013-1005, 12 November, the latest one along the administrative simplification process undergoing in France. The Act sets as its aim to improve relationship between Public Administrations and citizens.
Alejandra Boto Álvarez
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

the Role of Leadership Styles, Organizational Culture and Organizational Trust on Organizational Silence (Case Study: Payame Noor University of Kermanshah Province) [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2018
The purpose of this research is the role of leadership styles, organizational culture and organizational trust on organizational silence in Payame Noor University of Kermanshah.
Bahman Saeedipour
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ADMINISTRATIVE SILENCE

open access: yes, 2016
Odlučujući o upravnoj stvari, javnopravno tijelo donosi rješenje, ali ako ovlašteno tijelo ne odluči o upravnoj stvari u zakonom propisanom roku, tada se govori o šutnji administracije, odnosno šutnji uprave.
Badanjak, Tihana
core  

Review of Administrative Justice in the Republic of Kosovo

open access: yesAcademicus International Scientific Journal, 2015
The present paper aims to provide a real view of adjudication of administrative cases in Kosovo. The issue of adjudication of administrative cases in the Republic of Kosovo remains a challenge following justice reforms which began in 2013 and are still ...
Islam Pepaj
doaj   +1 more source

Peer Coaching to Counteract Organizational Silence and Foster a Culture of Dialogue

open access: yesMedEdPORTAL, 2015
Dialogue is essential for transforming the culture of academic health centers, yet organizational silence is common. Senior faculty and administrative leaders can play key roles in building a healthier environment by not only developing their own skills ...
Mary Dankoski   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Use of Electronic Medical Records for Research: New Ethical Challenges and Possible Solutions

open access: yesActa Médica Portuguesa, 2019
Some clinicians feel that Ethics Committees act as a blockade to observational clinical studies. In the case of retrospective studies some have tried to solve this problem by reducing this sensitive data to simple administrative data in the hands of the ...
Carlos Meneses-Oliveira
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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