Results 41 to 50 of about 63,314 (226)

A1AR-ADN

open access: yes, 2021
* Simulations described in the following paper: Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia, CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai et. al.
Jinan Wang (6481673)   +1 more
core   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

GENES DEL COMPLEJO MAYOR DE HISTOCOMPATIBILIDAD (CMH), EN LA MORTALIDAD INFANTIL; HIPÓTESIS.

open access: yesMedicina, 2010
<p>El análisis del efecto de la raza (etnicidad) en la mortalidad infantil contradice la teoría genética y favorece mecanismos socioeconómicos. En este trabajo usamos la variabilidad genética, medida por los bloques genéticos HLA-DRB1*, DQB1*, de ...
Edmond J. Yunis   +5 more
doaj  

And then there was us Et puis nous sommes apparus

open access: yesJournal of the Royal Anthropological Institute, EarlyView.
In 1987, the academic conference ‘Origins and Dispersals of Modern Humans: Behavioural and Biological Perspectives’ was held in Cambridge, UK. Subsequently referred to as the ‘Human Revolution’ conference, this meeting brought together the most prominent academics working in the field of human origins, including archaeologists and palaeoanthropologists,
Emma E. Bird   +2 more
wiley   +1 more source

Estrategia de enseñanza de Biología Molecular para la edición genética In Silico: Una experiencia disruptiva

open access: yesRevista Ciencias Pedagógicas e Innovación, 2023
Las técnicas In silico se emplean para simular experimentos reales mediante herramientas computacionales en biología molecular. El objetivo de este estudio fue fomentar el uso de ensayos In silico en los estudiantes de la carrera de ingeniería en ...
Jessica Jacqueline Verdezoto Prado   +2 more
doaj   +1 more source

Gough's Cave and biomolecular archaeology: a story of evolving interpretation Archéologie biomoléculaire à la grotte de Gough's Cave : une interprétation en constante évolution

open access: yesJournal of the Royal Anthropological Institute, EarlyView.
Gough's Cave is a key archaeological site that has been at heart of British archaeology for the past century. Professor Chris Stringer, whom this special issue honours, has been a key figure in excavations and research projects at the site for many decades.
William A. Marsh
wiley   +1 more source

Enhanced fish detection sensitivity in aquatic systems using environmental RNA

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Environmental RNA (eRNA) can potentially augment the biological monitoring ability of the established environmental DNA (eDNA) application in conservation. Despite faster degradation, environmental RNA could offer unique advantages: it may help reduce the legacy signal compared to eDNA, provide insights into physiological status through gene ...
Ana Ramón‐Laca   +9 more
wiley   +1 more source

Los efectos personales en la identificación de personas desaparecidas en conflictos armados

open access: yesMaguaré, 2014
Se discute la pertinencia de los métodos tradicionales en la identificación de las personas desaparecidas en conflictos armados, a partir del análisis de los resultados de la exposición de los efectos personales de 67 restos de personas nn, que podrían ...
Edixon Quiñones Reyes
doaj   +2 more sources

From glacial echoes to timber pathways: Climatic–historical drivers and timber‐trade influence on the phylogeography of Ips sexdentatus in the Basque Country

open access: yesAgricultural and Forest Entomology, EarlyView.
Ips sexdentatus is expanding across southern Europe, attacking multiple Pinus species and showing the ability to colonize trees at early stages of decline. Genetic analysis of 668 individuals revealed 106 haplotypes, with Iberian populations as diversity hotspots, reflecting long‐term refugial persistence alongside more recent demographic expansion ...
Dimitrios N. Avtzis   +4 more
wiley   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani   +8 more
wiley   +1 more source

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