Results 61 to 70 of about 453,030 (311)

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu   +4 more
wiley   +1 more source

How to record an Adobe Connect session - PDF [PDF]

open access: yes, 2014
How to record an Adobe Connect ...
Abigail Ball
core  

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

Introduction to the Adobe Connect pods - PDF [PDF]

open access: yes, 2015
Introduction to the Adobe Connect ...
Abigail Ball
core  

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen   +16 more
wiley   +1 more source

Paisaje y diseño en torno a la construcción del templo de San Miguel Arcángel, Santo Domingo de Heredia, Costa Rica, 1879

open access: yesCuadernos Inter.c.a.mbio sobre Centroamérica y el Caribe, 2018
Este documento analiza los elementos del paisaje y del diseño alrededor de la construcción del templo patrimonial El Carmen (anterior ermita de San Miguel) durante el siglo XIX en Santo Domingo de Heredia, Costa Rica. Se utilizan las teorías del diseño y
Henry O. Vargas Benavides
doaj   +1 more source

Assessment of seismic performance of adobe structures in Pakistan and Portugal [PDF]

open access: yes, 2012
Adobe buildings exist in different parts of the world. The construction of these buildings can be carried out economically, using locally available materials and skills that do not require use of modern machinery.
Ahmed, M.   +5 more
core   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

How to set up an Adobe Connect room - PDF [PDF]

open access: yes, 2014
How to set up an Adobe Connect ...
Abigail Ball
core  

Atmahaú Pakmát [PDF]

open access: yes, 2017
A journey into the heart the US-Mexico borderlands reveals a world of ancient rivers, mud, and brick.Radio-Television ...
Quevedo, Cameron Gates
core   +1 more source

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