Results 61 to 70 of about 235,950 (316)

The Use of Steatite Powder Waste as an Aggregate for the Manufacture of Earth Blocks—An Evaluation of Its Impact on Physical, Mechanical and Thermal Conductivity Properties

Buildings
Earthen construction is a sustainable alternative to conventional building materials due to its low environmental impact; however, both its mechanical strength and durability differ from conventional building materials.
Carlos Alberto Casapino-Espinoza, José Manuel Gómez-Soberón, María Consolación Gómez-Soberón   +2 more
doaj   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

System Architecture and Prospective Evaluation Protocol of AskDoc: A Secure Multimodal mHealth Triage Assistant — Pilot Safety and Feasibility Study

Applied Medical Informatics
Aim: This study is explicitly designed as a feasibility and safety pilot, not a powered efficacy trial. Its dual purpose is: (i) to establish whether an AI-augmented, rule-constrained triage strategy can reduce clinically unsafe under-triage compared ...
Hema MADHAV, Vivin RAJAGOPALAN
doaj  

Más que adobes. La construcción con tierra durante los siglos IV-III a.C. en el Área 11 de Giribaile (Vilches, Jaén)

Lucentum, 2019
La campaña de excavación arqueológica desarrollada durante el año 2014 en la meseta de Giribaile documentó un espacio de almacenaje, el Área 11, en excelente estado de conservación que, entre otros materiales, ha proporcionado un total de 342 fragmentos ...
Antonio Jesús Ortiz Villarejo, Luis María Gutiérrez Soler, María Alejo Armijo   +2 more
doaj   +1 more source

Engineered Optogenetic Circuits In Yeast with Self‐Sustained Outputs

Advanced Science, EarlyView.
Optogenetic quorum‐sensing (OptoQS) circuit enables Saccharomyces cerevisiae to record transient light stimulus with self‐sustained outputs. Panel a indicates the design of the OptoQS circuit based on G‐protein coupled receptor (GPCR) signaling cascade. Panel b indicates the mode of action of surrogate messenger‐mediated signal transmission at the cell
Cong Fan, Haofeng Chen, Yan Wang, Junyi Wang, Yueyang Chen, Yang Zhang, Jinting Guan, Jifeng Yuan   +7 more
wiley   +1 more source

Leveraging Life Cycle Cost Analysis (LCCA) for Optimized Decision Making in Adobe Construction Materials

Applied Sciences
Adobe construction is a longstanding practice in South America and is characterized by its affordability, accessibility, and ecological sustainability.
Jorge Albuja-Sánchez, Andreina Damián-Chalán   +1 more
doaj   +1 more source

El asentamiento orientalizante e ibérico antiguo de "La Rábita", Guardamar del Segura (Alicante). Avance de las excavaciones 1996-1998

Trabajos de Prehistoria, 1998
[es] Al sur de la desembocadura del río Segura, la excavación de La Rábita califal ha revelado la existencia, en el mismo lugar, de un establecimiento de época Orientalizante/Protoibérica e Ibérica Antigua. El hábitat, cuya historia empieza probablemente
Rafael Azuar, Pierre Rouillard, Eric Gailledrat, Pierre Moret, Feliciana Sala Selles, Alain Badie   +5 more
doaj   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

Advanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source