Results 31 to 40 of about 443,616 (316)

Ontogeny of sex differences in response to novel objects from adolescence to adulthood in Lister-hooded rats

, 2011
This work was supported by The Wellcome Trust [grant 078405/Z/05/Z]n humans, novelty-seeking behavior peaks in adolescence and is higher in males than females.
Gillian R. Brown, Brown, Gillian Ruth, De‐Laine M. Cyrenne, Cyrenne, De-Laine   +3 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

TA Treatment of Depression. A Simplified Hermeneutic Single-Case Efficacy Design. The Case of “Giovanni”

International Journal of Transactional Analysis Research, 2019
This study is inspired by previous case series replications of Hermeneutic Single-Case Efficacy Design which aim was to evaluate the effectiveness of a manualized transactional analysis treatment for depressive disorders and depressive personality.
Mariavittoria Zanchetta, Laura Farina, Stefano Morena, Enrico Benelli   +3 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Distinct clinical phenotypes of pediatric Obsessive-Compulsive Disorder with and without neurodevelopmental disorders: evidence for a neurodevelopmental continuum

Journal of Neurodevelopmental Disorders
This study aimed to investigate clinical, demographic, and psychopathological differences between pediatric patients with obsessive-compulsive disorder (OCD) with and without comorbid neurodevelopmental disorders (NDDs), focusing on symptom presentation,
Barbara D’Aiello, Maria Pontillo, Francesco Demaria, Michelangelo Di Luzio, Cristina Di Vincenzo, Ilaria Bertoncini, Valeria Villani, Deny Menghini, Stefano Vicari   +8 more
doaj   +1 more source

Comprehensive sexuality education for the most disadvantaged young people: findings from formative research in Ethiopia

Sexual and Reproductive Health Matters, 2023
Comprehensive sexuality education (CSE) seeks to improve young people’s knowledge, attitudes and practices in relation to sexual and reproductive health, sexual and social relationships, and dignity and rights. In Ethiopia, young people with disabilities
Kate Pincock, Workneh Yadete, Darwit Girma, Nicola Jones   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A replication study to evaluate parental internalizing symptoms as predictors of anxiety symptoms

Cogent Psychology
Parental internalizing symptoms have been linked to children’s anxiety symptoms, but findings on the differential influence of mothers and fathers symptoms are mixed.
Thomas B. Bertelsen, Åshild Tellefsen Håland   +1 more
doaj   +1 more source