Results 1 to 10 of about 238,368 (308)

Transition to Psychosis in Individuals at Clinical High Risk: Meta-analysis

European Psychiatry, 2023
Introduction Estimating the current likelihood of transitioning from a clinical high risk for psychosis (CHR-P) to psychosis holds paramount importance for preventive care and applied research.
G. Salazar De Pablo, J. Radua, I. Bonoldi, V. Arienty, F. Besana, A. Cabras, A. Catalan, P. Fusar-Poli   +7 more
doaj   +1 more source

Delving into the world of webCHAT – an e-mental health support service for distressed youths in Singapore

Digital Health
Background Young people face high rates of mental health issues, yet many do not seek professional help. In 2017, CHAT launched webCHAT – a free, anonymous, one-on-one synchronous web-based text service managed by case managers (CMs) to support young ...
Yi Ping Lee, Ying Ying Lee, Hamidah Binte Otheman, Charmaine Tang, Mythily Subramaniam, Swapna K Verma   +5 more
doaj   +1 more source

Successful switching from risperidone to cariprazine in a schizophrenic patient with pronounced functional deficit. Case report

Frontiers in Psychiatry, 2023
A 22-year-old male was admitted to an in-patient psychiatric unit for treatment, after a period of 2 years of increasing psychotic symptoms corresponding to a very severe case of schizophrenia across the entire scale of symptom disorder domains along ...
Johan Sahlsten Schölin, José Rodriguez Cruz, Stephan Hjorth   +2 more
doaj   +1 more source

Machine learning for brain age prediction: Introduction to methods and clinical applications

EBioMedicine, 2021
The rise of machine learning has unlocked new ways of analysing structural neuroimaging data, including brain age prediction. In this state-of-the-art review, we provide an introduction to the methods and potential clinical applications of brain age ...
Lea Baecker, Rafael Garcia-Dias, Sandra Vieira, Cristina Scarpazza, Andrea Mechelli   +4 more
doaj   +1 more source

The Implementation and Review of Cognitive Remediation Training for First Episode Psychosis in Singapore

Frontiers in Psychiatry, 2021
Objective: Early intervention in patients with first episode psychosis (FEP) can improve cognitive abilities, with both short- and long-term benefits. In this paper, we describe the implementation and review of cognitive remediation training (CRT) in an ...
Nigel Ian Ming Chong, Yogeswary Maniam, Yi Chian Chua, Charmaine Tang   +3 more
doaj   +1 more source

Ten year neurocognitive trajectories in first-episode psychosis

Frontiers in Human Neuroscience, 2013
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant ...
Helene Eidsmo Barder, Helene Eidsmo Barder, Helene Eidsmo Barder, Kjetil eSundet, Kjetil eSundet, Bjørn eRund, Bjørn eRund, Julie eEvensen, Julie eEvensen, Ulrik eHaahr, Wenche eHegelstad, Inge eJoa, Jan Olav eJohannessen, Jan Olav eJohannessen, Johannes eLangeveld, Tor Ketil eLarsen, Tor Ketil eLarsen, Ingrid eMelle, Ingrid eMelle, Stein eOpjordsmoen, Stein eOpjordsmoen, Jan Ivar eRøssberg, Jan Ivar eRøssberg, Erik eSimonsen, Per eVaglum, Thomas eMcGlashan, Svein eFriis, Svein eFriis   +27 more
doaj   +1 more source

Sex Selection Bias in Schizophrenia Antipsychotic Trials—An Update Systematic Review

Women, 2021
The lack of female participation in antipsychotic trials for schizophrenia poses an important issue regarding its applicability, with direct and real-life repercussions to clinical practice. Here, our aim is to systematically review the sampling sex bias
Lais Fonseca, Viviane Machado, Yaskara C. Luersen, Felipe Paraventi, Larissa Doretto, Ana Cristina Chaves   +5 more
doaj   +1 more source

Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia

BJPsych Open, 2017
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service.
Jessica Foster, John Lally, Victoria Bell, Sukhi Shergill   +3 more
doaj   +1 more source

Remission with or without comorbid substance use disorders in early psychosis: long-term outcome in integrated care (ACCESS III study)

Frontiers in Psychology, 2023
IntroductionSchizophrenia-Spectrum-Disorders are associated with poor long-term outcome as well as disability and often severely affect the lives of patients and their families often from symptom onset. Up to 70% of first episode psychosis (FEP) patients
Friederike Rühl, Martin Lambert, Anja Rohenkohl, Vivien Kraft, Anne Daubmann, Brooke C. Schneider, Daniel Luedecke, Anne Karow, Jürgen Gallinat, Gregor Leicht, Daniel Schöttle   +10 more
doaj   +1 more source

Biological Predictors of Clozapine Response: A Systematic Review

Frontiers in Psychiatry, 2018
Background: Clozapine is the recommended antipsychotic for treatment-resistant schizophrenia (TRS) but there is significant variability between patients in the degree to which clozapine will improve symptoms.
Ruta Samanaite, Amy Gillespie, Amy Gillespie, Kyra-Verena Sendt, Grant McQueen, James H. MacCabe, Alice Egerton   +6 more
doaj   +1 more source