Results 21 to 30 of about 241,274 (304)

Reading emotions from body movement: a generalized impairment in schizophrenia

Frontiers in Psychology, 2016
Body language reading is a social cognitive process with importance for successful maneuvering of social situations. In this study, we investigated body language reading as assessed with human point-light displays in participants with a diagnosis of ...
Anja eVaskinn, Anja eVaskinn, Kjetil eSundet, Kjetil eSundet, Tiril eØstefjells, Tiril eØstefjells, Katharina eNymo, Katharina eNymo, Ingrid eMelle, Ingrid eMelle, Torill eUeland, Torill eUeland   +11 more
doaj   +1 more source

Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report

BMC Pharmacology and Toxicology, 2020
Background Acute pancreatitis is a rare but recognised complication of clozapine leading to termination of treatment. Case presentation We present the case of a 39-year-old man with treatment-resistant schizoaffective disorder and a history of recurrent ...
Victoria Rodriguez, Kieran Hanley, Ana Julia Arias, Diego Quattrone, Joseph Kuforiji, Eromona Whiskey, Sukhi S. Shergill   +6 more
doaj   +1 more source

Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia

npj Schizophrenia, 2022
The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N ...
Fanni Krajner, Laila Hadaya, Grant McQueen, Kyra-Verena Sendt, Amy Gillespie, Alessia Avila, John Lally, Emily P. Hedges, Kelly Diederen, Oliver D. Howes, Gareth J. Barker, David J. Lythgoe, Matthew J. Kempton, Philip McGuire, James H. MacCabe, Alice Egerton   +15 more
doaj   +1 more source

Brain structural and neurofunctional correlates of liability to psychosis : a multimodal neuroimaging approach [PDF]

, 2011
Schizophrenia is one of the most debilitating and still not entirely understood mental diseases. Improvements in the treatment came hand in hand with an introduction of antipsychotics and thus with better understanding of neurobiology underlying its ...
Smieskova, Renata
core   +1 more source

Recently evolved human-specific methylated regions are enriched in schizophrenia signals

BMC Evolutionary Biology, 2018
Background One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution.
Niladri Banerjee, Tatiana Polushina, Francesco Bettella, Sudheer Giddaluru, Vidar M. Steen, Ole A. Andreassen, Stephanie Le Hellard   +6 more
doaj   +1 more source

Glutamate connectivity associations converge upon the salience network in schizophrenia and healthy controls

Translational Psychiatry, 2021
Alterations in cortical inter-areal functional connectivity, and aberrant glutamatergic signalling are implicated in the pathophysiology of schizophrenia but the relationship between the two is unclear.
Robert A. McCutcheon, Toby Pillinger, Maria Rogdaki, Juan Bustillo, Oliver D. Howes   +4 more
doaj   +1 more source

N-Methyl-D-Aspartate Receptor availability in First-Episode Psychosis: a multi-modal PET-MR brain imaging study

European Psychiatry, 2022
Introduction N-Methyl-D-Aspartate Receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. Objectives Our aim was to determine if NMDAR availability was lower in patients with first episode ...
K. Beck, A. Arumuham, S. Brugger, R. Mccutcheon, M. Veronese, S. Kaar, T. Pillinger, J. Stone, O. Howes   +8 more
doaj   +1 more source

Emotion and psychosis: Links between depression, self-esteem, negative schematic beliefs and delusions and hallucinations [PDF]

, 2006
Background: The role of emotion in psychosis is being increasingly recognised. Cognitive conceptualisations of psychosis (e.g. [Garety, P.A., Kuipers, E.K., Fowler, D., Freeman, D., Bebbington, P.E., 2001.
Fowler, DG, Smith, Ben, Dunn, Graham, Smith, B, Fowler, D G, Freeman, D, Kuipers, E, Bebbington, Paul, Garety, P, Fowler, David G., Dunn, G, Bashforth, H, Garety, Philippa, Freeman, Daniel, Bebbington, P, Garety, P; id_orcid, Bashforth, Hannah, Kuipers, E; id_orcid, Kuipers, Elizabeth   +18 more
core   +1 more source

Psychosis-associated DNA methylomic variation in Alzheimer’s disease cortex [PDF]

, 2020
Psychotic symptoms are a common and debilitating feature of Alzheimer’s disease, associated with a more rapid course of decline. Current evidence from post-mortem and neuroimaging studies implicates frontal, temporal and parietal lobes, with reported ...
SE Pishva (21910730), W Viechtbauer (13398858), B Creese (16356432), A Smith (7678280), DLA van den Hove (17011731), C Ballard (7779416), P Proitsi (7719863), J Mill (17767260), K Lunnon (18628609)   +8 more
core   +5 more sources

Predicting psychosis in at-risk patients using abnormal neural oscillations and synchrony in conjunctions with machine learning algorithms [PDF]

, 2016
In the last 20 years, there has been a marked increase in interest in the early detection and treatment of psychosis. Despite the various potential “prodromes” that have been identified and have helped to increase the accuracy in the detection of persons
Ramyead, Avinash
core   +1 more source