Results 21 to 30 of about 207,623 (218)

An Exploration of Emotion Regulation in Psychosis [PDF]

, 2009
The emotional experience of individuals who experience psychosis has historically been neglected, possibly due to the divide between the psychoses and neuroses.
Harper, Sean, Gillanders, David, Livingstone, Karen   +2 more
core   +1 more source

Glutamate connectivity associations converge upon the salience network in schizophrenia and healthy controls

Translational Psychiatry, 2021
Alterations in cortical inter-areal functional connectivity, and aberrant glutamatergic signalling are implicated in the pathophysiology of schizophrenia but the relationship between the two is unclear.
Robert A. McCutcheon, Toby Pillinger, Maria Rogdaki, Juan Bustillo, Oliver D. Howes   +4 more
doaj   +1 more source

Predicting psychosis in at-risk patients using abnormal neural oscillations and synchrony in conjunctions with machine learning algorithms [PDF]

, 2016
In the last 20 years, there has been a marked increase in interest in the early detection and treatment of psychosis. Despite the various potential “prodromes” that have been identified and have helped to increase the accuracy in the detection of persons
Ramyead, Avinash
core   +1 more source

Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report

BMC Pharmacology and Toxicology, 2020
Background Acute pancreatitis is a rare but recognised complication of clozapine leading to termination of treatment. Case presentation We present the case of a 39-year-old man with treatment-resistant schizoaffective disorder and a history of recurrent ...
Victoria Rodriguez, Kieran Hanley, Ana Julia Arias, Diego Quattrone, Joseph Kuforiji, Eromona Whiskey, Sukhi S. Shergill   +6 more
doaj   +1 more source

Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia

npj Schizophrenia, 2022
The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N ...
Fanni Krajner, Laila Hadaya, Grant McQueen, Kyra-Verena Sendt, Amy Gillespie, Alessia Avila, John Lally, Emily P. Hedges, Kelly Diederen, Oliver D. Howes, Gareth J. Barker, David J. Lythgoe, Matthew J. Kempton, Philip McGuire, James H. MacCabe, Alice Egerton   +15 more
doaj   +1 more source

Emotion and psychosis: Links between depression, self-esteem, negative schematic beliefs and delusions and hallucinations [PDF]

, 2006
Background: The role of emotion in psychosis is being increasingly recognised. Cognitive conceptualisations of psychosis (e.g. [Garety, P.A., Kuipers, E.K., Fowler, D., Freeman, D., Bebbington, P.E., 2001.
Fowler, DG, Smith, Ben, Dunn, Graham, Smith, B, Fowler, D G, Freeman, D, Kuipers, E, Bebbington, Paul, Garety, P, Fowler, David G., Dunn, G, Bashforth, H, Garety, Philippa, Freeman, Daniel, Bebbington, P, Garety, P; id_orcid, Bashforth, Hannah, Kuipers, E; id_orcid, Kuipers, Elizabeth   +18 more
core   +1 more source

Recently evolved human-specific methylated regions are enriched in schizophrenia signals

BMC Evolutionary Biology, 2018
Background One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution.
Niladri Banerjee, Tatiana Polushina, Francesco Bettella, Sudheer Giddaluru, Vidar M. Steen, Ole A. Andreassen, Stephanie Le Hellard   +6 more
doaj   +1 more source

N-Methyl-D-Aspartate Receptor availability in First-Episode Psychosis: a multi-modal PET-MR brain imaging study

European Psychiatry, 2022
Introduction N-Methyl-D-Aspartate Receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. Objectives Our aim was to determine if NMDAR availability was lower in patients with first episode ...
K. Beck, A. Arumuham, S. Brugger, R. Mccutcheon, M. Veronese, S. Kaar, T. Pillinger, J. Stone, O. Howes   +8 more
doaj   +1 more source

Ethnic variations in compulsory detention and hospital admission for psychosis across four UK Early Intervention Services [PDF]

, 2014
Substantial ethnic variations have been found in incidence, pathways to care and outcomes in psychosis. It is unknown whether these remain as marked in the presence of specialist Early Intervention Services (EIS) for psychosis.
Barnaby Major, Lawrence, J, Johnson, S, Joyce, John, Andrew Tapfumaneyi, Joyce, J, Fisher, Helen L; id_orcid, Jo Lawrence, Tapfumaneyi, A, Hinton, MF, Helen L Fisher, Lawrence, Jo, Hinton, Mark F, Sonia Johnson, John Joyce, Mark F Hinton, Johnson, Sonia, Fisher, HL, Mann, F, Farhana Mann, Major, Barnaby, Tapfumaneyi, Andrew, Major, B, Mann, Farhana   +23 more
core   +1 more source

Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions [PDF]

, 2006
Background. Assessing illness perceptions has been useful in a range of medical disorders. This study of people with a recent relapse of their psychosis examines the relationship between illness perception, their emotional responses and their attitudes ...
Garety, PA, Bebbington, P E, P. W. B. Watson, Freeman, D, Weinman, J, Weinman, J., Fowler, D., Dunn, G., Dunn, G, Bebbington, PE, D. Fowler, J. Weinman, G. Dunn, Garety, P A; id_orcid, Kuipers, E; id_orcid, Watson, PWB, Watson, PW, Fowler, D, Kuipers, E, Watson, P W B, E. Kuipers, Watson, P. W. B., Freeman, D., Bebbington, P. E., Freeman, Daniel, P. E. Bebbington, D. Freeman, P. A. Garety, Garety, P. A., Kuipers, E.   +29 more
core   +1 more source