Results 31 to 40 of about 354,339 (315)

Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: a multi-level modelling analysis [PDF]

, 2015
Background: Paranoia is one of the commonest symptoms of psychosis but has rarely been studied in a population at risk of developing psychosis. Based on existing theoretical models, including the proposed distinction between ‘poor me’ and ‘bad me ...
Bentall, R.P., Birchwood, M., Fowler, D., French, P., Gumley, A.I., Jones, P.B., Lewis, S.W., Morrison, A.P., Shryane, N., Stewart, S.L.K., Taylor, H.E.   +10 more
core   +2 more sources

Recently evolved human-specific methylated regions are enriched in schizophrenia signals

BMC Evolutionary Biology, 2018
Background One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution.
Niladri Banerjee, Tatiana Polushina, Francesco Bettella, Sudheer Giddaluru, Vidar M. Steen, Ole A. Andreassen, Stephanie Le Hellard   +6 more
doaj   +1 more source

A History of Trauma is Associated with Aggression, Depression, Non-Suicidal Self-Injury Behavior, and Suicide Ideation in First-Episode Psychosis. [PDF]

, 2019
The association between trauma and psychosis outcomes is well-established, and yet the impact of trauma on comorbid clinical symptoms-such as aggression, non-suicidal self-injury behavior (NSSIB), suicide ideation, and suicide behavior-for those with ...
Botello, Renata M, Carter, Cameron S, Grattan, Rebecca E, Lara, Natalia, Maguire, Adrienne M, Niendam, Tara A, Tryon, Valerie L   +6 more
core   +1 more source

Are informants required to obtain valid ratings on the Positive and Negative Syndrome Scale (PANSS)?

Schizophrenia, 2023
Ratings on the Positive and Negative Syndrome Scale (PANSS) are ideally based on both a patient interview and an informant questionnaire. In research and clinical settings, however, the informant questionnaire is often omitted.
Cecilie Marie Nielsen, Pernille Kølbæk, David Dines, Mark Opler, Christoph U. Correll, Søren Dinesen Østergaard   +5 more
doaj   +1 more source

Transition to Psychosis in Individuals at Clinical High Risk: Meta-analysis

European Psychiatry, 2023
Introduction Estimating the current likelihood of transitioning from a clinical high risk for psychosis (CHR-P) to psychosis holds paramount importance for preventive care and applied research.
G. Salazar De Pablo, J. Radua, I. Bonoldi, V. Arienty, F. Besana, A. Cabras, A. Catalan, P. Fusar-Poli   +7 more
doaj   +1 more source

Social fragmentation, deprivation and urbanicity: relation to first-admission rates for psychoses [PDF]

, 2005
<i>Declaration</i> <i>of</i> <i>interest</i>: None. <i>Background</i>: Social disorganisation, fragmentation and isolation have long been posited as influencing the rate of psychoses at area level ...
Carr-Hill, Carstairs, Faris, Harley, Harper Gilmour, Jacqueline Atkinson, Jennifer Bishop, Judith Allardyce, Kendrick, McLoone, Midwinter, R. G. McCreadie, Tracey Rapson   +12 more
core   +1 more source

Successful switching from risperidone to cariprazine in a schizophrenic patient with pronounced functional deficit. Case report

Frontiers in Psychiatry, 2023
A 22-year-old male was admitted to an in-patient psychiatric unit for treatment, after a period of 2 years of increasing psychotic symptoms corresponding to a very severe case of schizophrenia across the entire scale of symptom disorder domains along ...
Johan Sahlsten Schölin, José Rodriguez Cruz, Stephan Hjorth   +2 more
doaj   +1 more source

Delving into the world of webCHAT – an e-mental health support service for distressed youths in Singapore

Digital Health
Background Young people face high rates of mental health issues, yet many do not seek professional help. In 2017, CHAT launched webCHAT – a free, anonymous, one-on-one synchronous web-based text service managed by case managers (CMs) to support young ...
Yi Ping Lee, Ying Ying Lee, Hamidah Binte Otheman, Charmaine Tang, Mythily Subramaniam, Swapna K Verma   +5 more
doaj   +1 more source

Psychotic symptoms in young adults exposed to childhood trauma - A 20 year follow-up study [PDF]

, 2011
Childhood adversity has been shown to increase the risk of psychotic symptoms in adult life. However, there are no previous studies looking at the association between experiencing a natural disaster during childhood and the development of psychotic ...
Alexander McFarlane, Bak, Bebbington, Bolton, Bremner, Cantor-Graae, Cherrie Galletly, Cougnard, Degenhardt, Dominguez, Dragt, Dube, Goldney, Green, Guan, Hall, Houston, Issa, Janssen, Janssen, Jindal, Joordan, Lataster, Leeies, Liu, McFarlane, McFarlane, McFarlane, Miettunen, Miranda Van Hooff, Morgan, Morgan, Müller-Vahl, Parker, Rutter, Rutter, Salmon, Saunders, Soyka, Spauwen, Thompson, van Os, van Winkel, Velakoulis, Walker, World Health Organization, Yule   +46 more
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source