Results 91 to 100 of about 453,715 (289)

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

How are Scotland's young people doing? : A cross-national perspective on physical activity, TV viewing, eating habits, body image and oral hygiene [PDF]

, 2011
The HBSC study in Scotland is funded by NHS Health ...
Smith, R, Alexander, L, Currie, Candace, Todd, J   +3 more
core   +2 more sources

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Does your mother know? : parent-child communication about adolescent daily activities [PDF]

, 2010
Juvenile offending is a wide-spread problem in Western societies: More than half of the adolescents engage in minor forms of delinquency, and this causes high material and immaterial costs.
Dep Educatie & Pedagogiek, Leerstoel Meeus, Keijsers, L., Adolescent development: Characteristics and determinants   +3 more
core   +1 more source

Adolescent Ethnic Identity in Social Context: A Commentary [PDF]

, 2017
Key findings from the various studies of this special section of Child Development are that ethnic identity is embedded in a positive proximal interpersonal context in adolescence and that the links between ethnic identity and the interpersonal context ...
Meeus, W.H.J., Meeus, Wim, Leerstoel Meeus, Wim Meeus, Adolescent development: Characteristics and determinants   +4 more
core   +2 more sources

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu, Shuting Huang, Leilei Zhu, Junyi Huang, Kewei Li, Guangming Li, Jiannong Wu, Mingyuan Zhou, Fangmei Zhou, Zhishan Ding, Yingzhi Shen   +10 more
wiley   +1 more source

Sexualidade das adolescentes em situação de acolhimento: contexto de vulnerabilidade para DST [Sexuality of adolescent girls in foster care: context of vulnerability to STD]

Revista Enfermagem UERJ, 2015
As adolescentes em situação de acolhimento não fogem aos rótulos de adolescente; porém, tendo em vista seucontexto, têm maior vulnerabilidade às doenças sexualmente transmissíveis (DST).
Raquel Fonseca Rodrigues, Lucia Helena Garcia Penna, Liana Viana Ribeiro, Mírian Verdeno Paes, Claudia Rosane Guedes   +4 more
doaj  

Do Universal Free School Meals Improve the Dietary Quality of Food‐At‐Home Purchases?

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Since 2014, the number of schools offering universal free meals to all enrolled children without requiring annual meal applications has increased meaningfully. Using USDA's Purchase to Plate Crosswalk, a difference‐in‐differences framework, and a nationwide consumer panel, the effect of universal‐free‐meal exposure on the diet quality of food ...
Xueying Ma, Andres Cuadros‐Meñaca, Michael R. Thomsen   +2 more
wiley   +1 more source

Constructing and Validating New County‐Level Cultural Capital Indices for Applied Policy Analysis: Evidence From SNAP Take‐Up

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Cultural capital influences a wide range of social and economic outcomes, yet quantitative measures suitable for policy analysis remain limited. We develop county‐level cultural capital indices for the US based on Bourdieu's framework of objectified, embodied, and institutionalized cultural capital.
Pratyoosh Kashyap, Becca B. R. Jablonski, John Bovay   +2 more
wiley   +1 more source

Associations Between Multi-Level Contextual Factors and Mental Health Service Utilization in Adolescents with Comorbid Depression and Substance-use: Moderating role of School Connectedness on Racial/Ethnic Disparities in Service Utilization

Journal of the Georgia Public Health Association, 2017
Background: Comorbid depression and substance use has been a prevalent issue in adolescent health. Although rates have remained relatively stable, their level is still alarming and efforts to see a decrease have led leaders and organizations to call for ...
Kate Thornton
doaj   +1 more source