Results 71 to 80 of about 9,010 (258)

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Causes of Institutionalization of Children and Adolescents in a Shelter in Brazil

European Psychiatry, 2017
IntroductionA growing number of studies investigating the relationship between violence and problems in child psychiatry. Consistent findings have been verified in studies related to aggressive behavior, antisocial and post-traumatic stress disorder with the violence against children.
E. Guilherme, S.D. Dos Santos
openaire   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

AGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang, Bo Xie, Can Liu, Yifan Song   +3 more
wiley   +1 more source

Sexualidade das adolescentes em situação de acolhimento: contexto de vulnerabilidade para DST [Sexuality of adolescent girls in foster care: context of vulnerability to STD]

Revista Enfermagem UERJ, 2015
As adolescentes em situação de acolhimento não fogem aos rótulos de adolescente; porém, tendo em vista seucontexto, têm maior vulnerabilidade às doenças sexualmente transmissíveis (DST).
Raquel Fonseca Rodrigues, Lucia Helena Garcia Penna, Liana Viana Ribeiro, Mírian Verdeno Paes, Claudia Rosane Guedes   +4 more
doaj  

Mental Health Issues in Institutionalized Adolescent Orphans

International Journal of Indian Psychology, 2015
The aim of the study was to determine the nature and extend of Mental Health issues in institutionalized adolescent orphans of District Kupwara. A case study of orphans aged 11 to 17 years from 04 orphanages in Kupwara. A structured and internationally standardized interview schedule MINI Kid (Mini International Neuropsychiatric Interview for Kids) was
null Nasir Mohammad Bhat, null Dr. Sadaqat Rahman, null Aijaz Ahmed Bhat   +2 more
openaire   +1 more source

Age and Regional Trends in Groin Hernia Surgery in Japan: An Analysis of Laparoscopic Repair, Outpatient Surgery, and Manual Reduction Using National Database Open Data

Annals of Gastroenterological Surgery, EarlyView.
Using National Database open data from 2014 to 2023, this nationwide study visualizes age‐, sex‐, and region‐specific trends in groin hernia surgery in Japan. Laparoscopic surgery, outpatient surgery, and manual reduction were analyzed to estimate lifetime surgical burden and patterns of emergency‐related healthcare utilization at the population level.
Masanori Sato, Kyosuke Miyazaki, Tatsuya Tazaki, Itsuro Nagae, Taketo Matsubara, Saseem Poudel, Tsuyoshi Takagi, Hidetoshi Wada   +7 more
wiley   +1 more source

Associations Between Multi-Level Contextual Factors and Mental Health Service Utilization in Adolescents with Comorbid Depression and Substance-use: Moderating role of School Connectedness on Racial/Ethnic Disparities in Service Utilization

Journal of the Georgia Public Health Association, 2017
Background: Comorbid depression and substance use has been a prevalent issue in adolescent health. Although rates have remained relatively stable, their level is still alarming and efforts to see a decrease have led leaders and organizations to call for ...
Kate Thornton
doaj   +1 more source