Results 121 to 130 of about 872,005 (359)

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan   +13 more
wiley   +1 more source

Assessing the Link between Adolescent Fertility and Urban Crime [PDF]

open access: yes
We use data of neighborhoods of Bogotá to assess the causal relation between their adolescent fertility and their homicide rates. We find that neighborhoods with high adolescent fertility rates, and that have low secondary enrollment and high crime rates
Alejandro Gaviria   +2 more
core  

The Influence of Explainable Artificial Intelligence and Mental Health Literacy on Professional Psychological Help-Seeking Behavior: The Mediating Role of Psychological Problem Cognition

open access: yesBehavioral Sciences
Approximately 970 million people worldwide suffer from mental disorders, yet over 60% do not seek professional help. Key barriers include low mental health literacy (MHL), insufficient awareness of psychological issues, and the overwhelming and non ...
Weijun Wang   +3 more
doaj   +1 more source

Cross-cultural adaptation, validity, and reliability of the Child and Adolescent Behavior Inventory (CABI) for use in Brazil. [PDF]

open access: yesJ Pediatr (Rio J), 2023
Costa DS   +8 more
europepmc   +1 more source

Healthy or Unhealthy? The Cocktail of Health-Related Behavior Profiles in Spanish Adolescents [PDF]

open access: gold, 2019
Javier Sevil‐Serrano   +4 more
openalex   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

open access: yesAdvanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu   +7 more
wiley   +1 more source

Acceptance and utilization of web-based self-help for caregivers of children with externalizing disorders

open access: yesChild and Adolescent Psychiatry and Mental Health
Background Web-based self-help interventions for parents of children with ADHD and other externalizing disorders have been proven to be effective. In order to recommend individualized and optimized interventions, a better understanding of the acceptance ...
Laura Wähnke   +6 more
doaj   +1 more source

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