Results 121 to 130 of about 1,362,433 (302)

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Validation of the Thai Version of the Patient Health Questionnaire for Adolescents (PHQ-A) in adolescent psychiatric patients

International Journal of Child Development and Mental Health, 2020
A basic screening tool for depression for adolescents was insufficient in Thailand. Thus, Patient Health Questionnaire for Adolescents (PHQ-A) was translated into Thai.
Wimonwan Panyawong, Chosita Pavasuthipaisit, Rattanasak Santitadakul   +2 more
doaj  

National Adolescent Sexual and Reproductive Health Programme: Mid-Term Evaluation Report [PDF]

, 2013
EXECUTIVE SUMMARY Background and rationale Th e Ministry of Health and Population (MoHP) Nepal has endorsed the Nepal Health Sector Programme (NHSP) II (2010–2015), which aims to introduce 1,000 adolescent-friendly services (AFSs) in Nepal by 2015 ...
Khatri, R., Schildbach, E., Schmitz, K., Silwal, P.R., van Teijlingen, Edwin   +4 more
core  

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

Advanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever   +7 more
wiley   +1 more source

Stage- and sex-specific associations of prenatal individual and mixed metals exposure with adiposity peak and adiposity rebound among children: a prospective birth cohort study

BMC Medicine
Background Adiposity peak (AP) and adiposity rebound (AR) are key indicators of early childhood growth, which are closely related to obesity, premature puberty, and metabolic abnormalities.
Yingying Zuo, Yanyan Jiang, Xing Wang, Chunmei Liang, Cong Geng, Jixing Zhou, Xingyong Tao, Kun Huang, Xiaoyan Wu, Fangbiao Tao, Juan Tong   +10 more
doaj   +1 more source

Effectiveness of education and training programmes to help clinicians assess and classify perineal tears: a systematic review

BMJ Open
Objective For every 100 women having a vaginal birth, approximately four will experience a severe (third-degree or fourth-degree) perineal tear. Severe perineal tears are associated with significant short-term and long-term consequences if not recognised
Caroline Homer, Alyce N Wilson, Alexander John Eggleston, Annabel Richards, Grace Simpson, Joshua Peter Vogel, Moira Philip   +6 more
doaj   +1 more source

Adolescent Refugees Resettled in Philadelphia: A Qualitative Study with Key Informants [PDF]

, 2018
More than 22.5 million refugees are currently displaced globally, with refugees below the age of 18 years old making up more than half of this population. More than 3,600 have been resettled in Pennsylvania as of 2016, 875 in Philadelphia County.
Fogg, MSW, Melissa, Frasso, PhD, CPH, Rosemary, Ghosh, MPHc, Pia, Plumb, MD, Ellen   +3 more
core   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Effects of Early-Adolescent, Mid-Adolescent, or Adult Stress on Morphine Conditioned Place Preference [PDF]

, 2017
Early-life stress is correlated with negative mental health outcomes, including illicit drug abuse. One mechanism that may contribute to drug abuse is stress-induced elevation of drug reward.
Bakner, Lee, Becker, Sarah, Shields, Chloe N.   +2 more
core   +1 more source