Results 91 to 100 of about 2,501,354 (348)

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Mobile exergaming in adolescents’ everyday life—contextual design of where, when, with whom, and how: the SmartLife case [PDF]

, 2018
Exergames, more specifically console-based exergames, are generally enjoyed by adolescents and known to increase physical activity. Nevertheless, they have a reduced usage over time and demonstrate little effectiveness over the long term.
Cardon, Greet, Chastin, Sebastien, Costa, Ruben, DeSmet, Ann, Domenech, Jorge, Ferri, Josue, Grilo, António, Schwarz, Ayla, Stragier, Jeroen   +8 more
core   +3 more sources

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Health concerns of Iranian adolescents: Protocol for a mixed methods study [PDF]

, 2014
Background: Adolescents have particular health and developmental needs that suggest they should neither be treated as older children nor younger adults. Objectives: The aim of this paper is to report the protocol for a mixed methods study that set out to
Ahmadi, F., Baheiraei, A., Foroushani, A.R., Ghofranipour, F., Khoori, E.   +4 more
core   +2 more sources

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Preparing adolescents attending progressive and no-excuses urban charter schools to analyze, navigate, and challenge race and class inequality [PDF]

, 2016
Background/Context: Sociopolitical development (SPD) refers to the processes by which an individual acquires the knowledge, skills, emotional faculties, and commitment to recognize and resist oppressive social forces.
Clark, Shelby, El-Amin, Aaliyah, Gramigna, Kathryn, Graves, Daren, Jennett, Pauline, Kenslea, Megan, Seider, Scott, Sklarwitz, Sherri, Soutter, Madora, Tamerat, Jalene, Yung, Jennifer   +10 more
core  

Psychohygienic Aspects Of Training Of Disabled Adolescents With Pathology Of The Vision [PDF]

, 2017
The objective of this article is to undertake a literature review to familiarize ourselves with the knowledge base; to summarize information about some psycho-hygienic aspects of teaching and visually impaired adolescents, including features of ...
Sasina, O. (Olga)
core   +2 more sources

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

Prevalence of Ocular Morbidity Among School Adolescents of Gandhinagar District, Gujarat [PDF]

, 2011
Objective: To study the prevalence of ocular morbidity (abnormal condition) and various factors affecting it among school attending adolescents. Methods: A cross-sectional study was conducted to study abnormal ocular conditions like refractive errors ...
Chudasama, Rajesh K, Kedia, Geeta, Oza, Jaydeep, Prajapati, Jagruti, Prajapati, Prakash   +4 more
core   +1 more source