Results 51 to 60 of about 3,344,927 (305)

A proposal for a brief-term post-adoption intervention in the attachment-perspective: a single case study with a late-adopted child and his adoptive mother

open access: yesResearch in Psychotherapy, 2016
A growing body of attachment literature has focused on bridging the gap between research and clinical applications, even in clinical work with adoptive families.
Cecilia Serena Pace   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Balinese Customary Law Perspective on The Existence of Adopted Children

open access: yesSociological Jurisprudence Journal
This research was conducted to find out what the inheritance rights of adopted children are regarding the existence of the inheritance of their adoptive parents according to Balinese customary law and what the position of adopted children is in the ...
I Nyoman Budiana   +1 more
doaj   +1 more source

Child defecation, feces disposal practices and associated factors in community-led total sanitation adopted districts in Jimma Zone, Ethiopia

open access: yesEnvironmental Challenges, 2021
Waste from infected individuals can contaminate the soil and water of the community without adequate sanitation facilities, increasing the risk of infection for other individuals.
Negasa Eshete Soboksa   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Meitheal and child and family support networks: process and outcomes study

open access: yes, 2018
This report presents research on the Meitheal and Child and Family Support Network (CFSN) model. The research has three components – (1) the Meitheal Process and Outcomes study, (2) findings on the Child and Family Support Networks and (3) Interviews ...
Rodriguez, Leonor   +2 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Parenting Your Adopted School-Aged Child

open access: yes, 2020
This factsheet is designed to help adoptive parents understand and respond to their school-age child\u27s developmental needs. It provides simple, practical strategies you can use to foster healthy development, including approaches for building ...
Child Welfare Information Gateway
core   +1 more source

Legal Implementation of the Cancellation of Grants to Adoptive Children who Neglect the Grantor Based on the Civil Code

open access: yesInternational Journal of Islamic Education, Research and Multiculturalism
In the case of the above decision, the judge granted the plaintiff's claim to cancel the grant deed and the grant object returned to the rights of the grantor.
Nita Kusumawati   +2 more
doaj   +1 more source

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