Results 41 to 50 of about 86,483 (289)

Nation-scale adoption of new medicines by doctors: an application of the Bass diffusion model

open access: yesBMC Health Services Research, 2012
Background The adoption of new medicines is influenced by a complex set of social processes that have been widely examined in terms of individual prescribers’ information-seeking and decision-making behaviour.
Dunn Adam G   +5 more
doaj   +1 more source

Localization and mimetic adoption in norm diffusion: ASEAN’s amity and cooperation norm for the Indo-Pacific

open access: yesCogent Social Sciences, 2023
The ASEAN Outlook on the Indo-Pacific became the foundation of ASEAN’s diffusion of amity and cooperation norms in the wider Indo-Pacific region. However, a gap in the literature indicates a lack of understanding of the process and phases of the norm ...
Bama Andika Putra
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Correlation between Perceived Attributes of Evidence Based Practice and Its Adoption in Baccalaureate Nursing Students Based on Rogers\'s Diffusion of Innovation [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2014
Introduction: Evidence based practice (EBP) is an essential in nursing education. Several factors affect the adoption of education and practice that Rogers's Diffusion of Innovation explains them.
Tahereh Ashktorab   +3 more
doaj  

Policy diffusion in federal systems during a state of emergency: diffusion of COVID-19 statewide lockdown policies across the United States

open access: yesStudia z Polityki Publicznej, 2022
This paper develops a unified model of policy diffusion to analyze the speed of adoption of statewide lockdown policies within a federal system during the COVID-19 pandemic.
Sharon Elhadad, Udi Sommer
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Diffusion mechanism of green building in industrial clusters: An agent-based modeling approach

open access: yesDevelopments in the Built Environment
Industrial clusters are conducive to accelerating the adoption of green technologies and green buildings, but the underlying mechanism of cluster-based adoption among different stakeholders is seldom examined.
Mi Pan, Xiaojing Zhao, Zhaotong Li
doaj   +1 more source

A System Dynamics Model for the Diffusion of Cloud Manufacturing Mode With Evolutionary Game Theory

open access: yesIEEE Access, 2021
Cloud manufacturing (CMfg) is emerging as an advanced green and efficient manufacturing mode for the manufacturing industry. It has gained extensive attentions owing to the unique manufacturing mode and advantages.
Tianri Wang, Chao Li, Pengzhi Zhang
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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