Nation-scale adoption of new medicines by doctors: an application of the Bass diffusion model
Background The adoption of new medicines is influenced by a complex set of social processes that have been widely examined in terms of individual prescribers’ information-seeking and decision-making behaviour.
Dunn Adam G +5 more
doaj +1 more source
The ASEAN Outlook on the Indo-Pacific became the foundation of ASEAN’s diffusion of amity and cooperation norms in the wider Indo-Pacific region. However, a gap in the literature indicates a lack of understanding of the process and phases of the norm ...
Bama Andika Putra
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Correlation between Perceived Attributes of Evidence Based Practice and Its Adoption in Baccalaureate Nursing Students Based on Rogers\'s Diffusion of Innovation [PDF]
Introduction: Evidence based practice (EBP) is an essential in nursing education. Several factors affect the adoption of education and practice that Rogers's Diffusion of Innovation explains them.
Tahereh Ashktorab +3 more
doaj
This paper develops a unified model of policy diffusion to analyze the speed of adoption of statewide lockdown policies within a federal system during the COVID-19 pandemic.
Sharon Elhadad, Udi Sommer
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Diffusion mechanism of green building in industrial clusters: An agent-based modeling approach
Industrial clusters are conducive to accelerating the adoption of green technologies and green buildings, but the underlying mechanism of cluster-based adoption among different stakeholders is seldom examined.
Mi Pan, Xiaojing Zhao, Zhaotong Li
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A System Dynamics Model for the Diffusion of Cloud Manufacturing Mode With Evolutionary Game Theory
Cloud manufacturing (CMfg) is emerging as an advanced green and efficient manufacturing mode for the manufacturing industry. It has gained extensive attentions owing to the unique manufacturing mode and advantages.
Tianri Wang, Chao Li, Pengzhi Zhang
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

